GR148672X

Modify Date: 2024-04-03 14:51:51

GR148672X Structure
GR148672X structure
Common Name GR148672X
CAS Number 263890-70-6 Molecular Weight 340.320
Density 1.4±0.1 g/cm3 Boiling Point 394.6±52.0 °C at 760 mmHg
Molecular Formula C15H11F3N2O2S Melting Point N/A
MSDS N/A Flash Point 192.4±30.7 °C

 Use of GR148672X


GR148672X is a triacyglycerol hydrolase (TGH) inhibitor with an IC50 of 4 nM extracted from patent WO 2001016358 A2.

 Names

Name 4,4,4-trifluoro-2-[(3-methylphenyl)hydrazinylidene]-1-thiophen-2-ylbutane-1,3-dione
Synonym More Synonyms

 GR148672X Biological Activity

Description GR148672X is a triacyglycerol hydrolase (TGH) inhibitor with an IC50 of 4 nM extracted from patent WO 2001016358 A2.
Related Catalog
Target

IC50: 4 nM (TGH)[1]

References

[1]. Catherine Sylvia Borg-Capra, et al. Method of screening for triacyglycerol hydrolase inhibitors . WO 2001016358 A2.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 394.6±52.0 °C at 760 mmHg
Molecular Formula C15H11F3N2O2S
Molecular Weight 340.320
Flash Point 192.4±30.7 °C
Exact Mass 340.049347
PSA 86.77000
LogP 4.18
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.575
Storage condition 2-8℃

 Synonyms

(2E)-4,4,4-Trifluoro-2-[(3-methylphenyl)hydrazono]-1-(2-thienyl)-1,3-butanedione
4,4,4-trifluoro-2-[2-(3-methylphenyl)hydrazono]-1-(2-thienyl)butane-1,3-dione
1,2,3-Butanetrione, 4,4,4-trifluoro-1-(2-thienyl)-, 2-[2-(3-methylphenyl)hydrazone], (2E)-
GR148672X