Axl-IN-6

Modify Date: 2025-09-28 18:22:37

Axl-IN-6 structure	Common Name	Axl-IN-6
	CAS Number	2642224-22-2	Molecular Weight	492.65
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₂H₃₆N₄O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Axl-IN-6

Axl-IN-6 (compound 14) is an orally active and potent AXL inhibitor. Axl-IN-6 is well tolerated and significantly inhibits the tumor growth in MV-4-11 subcutaneous xenograft model[1].

Name	Axl-IN-6

Description	Axl-IN-6 (compound 14) is an orally active and potent AXL inhibitor. Axl-IN-6 is well tolerated and significantly inhibits the tumor growth in MV-4-11 subcutaneous xenograft model[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> TAM Receptor
Target	AXL[1]
References	[1]. Zhang LL, et al. Discovery a series of quinazolin derivatives as potent AXL inhibitors. Eur J Med Chem. 2022 Apr 6;237:114316.[published online ahead of print, 2022 Apr 6]. Eur J Med Chem. 2022;237:114316.

Molecular Formula	C₃₂H₃₆N₄O
Molecular Weight	492.65
InChIKey	SACMJOUEIQIULE-NDEPHWFRSA-N
SMILES	CC(C)Oc1ccc(-c2cccc3cnc(Nc4ccc5c(c4)CCC(N4CCCC4)CC5)nc23)cc1

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