TLR7/8 agonist 9

Modify Date: 2025-08-25 12:24:53

TLR7/8 agonist 9 structure	Common Name	TLR7/8 agonist 9
	CAS Number	2649170-17-0	Molecular Weight	366.46
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₂₆N₆O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of TLR7/8 agonist 9

TLR7/8 agonist 9 (Compound 25a) is a TLR7/8 agonist, with EC50s of 40 nM and 23 nM for hTLR7/8. TLR7/8 agonist 9 has anti-tumor activity and improves the antitumor activity of PD-1/PD-L1 blockade. TLR7/8 agonist 9 can be used for research of cancer immunotherapy[1].

Name	TLR7/8 agonist 9

Description	TLR7/8 agonist 9 (Compound 25a) is a TLR7/8 agonist, with EC50s of 40 nM and 23 nM for hTLR7/8. TLR7/8 agonist 9 has anti-tumor activity and improves the antitumor activity of PD-1/PD-L1 blockade. TLR7/8 agonist 9 can be used for research of cancer immunotherapy[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR) Research Areas >> Cancer
Target	EC50s: 40 nM and 23 nM for hTLR7/8[1]
References	[1]. Wang Z, et al. Structure-Based Design of Highly Potent Toll-like Receptor 7/8 Dual Agonists for Cancer Immunotherapy. J Med Chem. 2021 Jun 10;64(11):7507-7532.

Molecular Formula	C₂₀H₂₆N₆O
Molecular Weight	366.46

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TLR7/8 agonist 9

Use of TLR7/8 agonist 9

Names

TLR7/8 agonist 9 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.