FD2056
Modify Date: 2025-08-25 18:55:58
FD2056 structure
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Common Name | FD2056 | ||
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| CAS Number | 2685870-87-3 | Molecular Weight | 476.94 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H17ClN6O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of FD2056FD2056 is a potent and orally active PI3K inhibitor. FD2056 inhibits PI3Kα/PI3Kβ/PI3Kγ/PI3Kδ with IC50s of 0.30, 0.80, 1.10, 0.42 nM. FD2056 also inhibits CDK2-CyclinA2 and CDK4-CyclinD3 with IC50 of 115.95 and 2782.15 nM. FD2056 inhibits breast cancer cell proliferation with IC50s of 1.06, 0.04, 1.40 μM for MDA-MB-231, MDA-MB-468, MCF-7 cells. FD2056 also induces cancer apoptosis and inhibits tumor growth[1]. |
| Name | FD2056 |
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| Description | FD2056 is a potent and orally active PI3K inhibitor. FD2056 inhibits PI3Kα/PI3Kβ/PI3Kγ/PI3Kδ with IC50s of 0.30, 0.80, 1.10, 0.42 nM. FD2056 also inhibits CDK2-CyclinA2 and CDK4-CyclinD3 with IC50 of 115.95 and 2782.15 nM. FD2056 inhibits breast cancer cell proliferation with IC50s of 1.06, 0.04, 1.40 μM for MDA-MB-231, MDA-MB-468, MCF-7 cells. FD2056 also induces cancer apoptosis and inhibits tumor growth[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C23H17ClN6O2S |
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| Molecular Weight | 476.94 |
| InChIKey | FGIXGBJDHZFADD-UHFFFAOYSA-N |
| SMILES | Nc1cc(-c2c[nH]c3ncc(-c4cnc(Cl)c(NS(=O)(=O)c5ccccc5)c4)cc23)ccn1 |