4H-1,3,2-Oxazaphosphorin-4-one,2-[bis(2-chloroethyl)amino]tetrahydro-, 2-oxide

Modify Date: 2025-08-20 23:16:19

4H-1,3,2-Oxazaphosphorin-4-one,2-[bis(2-chloroethyl)amino]tetrahydro-, 2-oxide structure	Common Name	4H-1,3,2-Oxazaphosphorin-4-one,2-[bis(2-chloroethyl)amino]tetrahydro-, 2-oxide
	CAS Number	27046-19-1	Molecular Weight	276.05400
	Density	1.42g/cm3	Boiling Point	N/A
	Molecular Formula	C₇H₁₂Cl₂NO₄P	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Name	2-[bis(2-chloroethyl)amino]-2-oxo-1,3,2λ5-oxazaphosphinan-4-one
Synonym	More Synonyms

Density	1.42g/cm3
Molecular Formula	C₇H₁₂Cl₂NO₄P
Molecular Weight	276.05400
Exact Mass	274.98800
PSA	65.65000
LogP	1.49000
Index of Refraction	1.515
Storage condition	-20°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RQ5857500

CHEMICAL NAME :: 4H-1,3,2-Oxazophosphorin-4-one, 2-(bis(2-chloroethyl)amino)tetrahydro-, 2-oxide

CAS REGISTRY NUMBER :: 27046-19-1

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C7-H13-Cl2-N2-O3-P

MOLECULAR WEIGHT :: 275.09

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Human Lymphocyte

DOSE/DURATION :: 100 umol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 129,47,1984

Cyclophosphamide

CAS#:50-18-0

Tetrahydro-2-(b...

CAS#:40277-05-2

2H-1,3,2-Oxazap...

CAS#:51274-71-6

4H-1,3,2-Oxazap...

CAS#:27046-19-1

Literature: Struck, Robert Frederick Patent: US2010/234325 A1, 2010 ; Location in patent: Page/Page column 2 ;

3-(benzyloxy)cy...

CAS#:78336-01-3

4H-1,3,2-Oxazap...

CAS#:27046-19-1

Literature: Brandt, Joan A.; Ludeman, Susan Marie; Zon, Gerald; Todhunter, John A.; Egan, William; Dickerson, Ruth Journal of Medicinal Chemistry, 1981 , vol. 24, # 12 p. 1404 - 1408

Cyclophosphamide

CAS#:50-18-0

~58%

4H-1,3,2-Oxazap...

CAS#:27046-19-1

Literature: Brandt, Joan A.; Ludeman, Susan Marie; Zon, Gerald; Todhunter, John A.; Egan, William; Dickerson, Ruth Journal of Medicinal Chemistry, 1981 , vol. 24, # 12 p. 1404 - 1408

Cyclophosphamide

CAS#:50-18-0

Propanoic acid,...

CAS#:22788-18-7

aldophosphamide

CAS#:35144-64-0

Tetrahydro-2-(b...

CAS#:40277-05-2

Detail

Literature: Wagner; Heydrich; Bartels; Hohorst Arzneimittel-Forschung, 1980 , vol. 30, # 9 p. 1588 - 1592

Precursor 2
CAS#:50-18-0 Cyclophosphamide CAS#:78336-01-3 3-(benzyloxy)cy...
DownStream 0

Oxo-Endoxan

4-Ketocyclophosphonamid

4-Ketocyclophosphamide

2-(Bis(2-chloroethyl)amino)tetrahydro-4H-1,3,2-oxazaphosphorin-4-one 2-oxide

4-ketocyclophosphamide mustard

Asta 5160

4H-1,3,2-Oxazophosphorin-4-one,2-(bis(2-chloroethyl)amino)tetrahydro-,2-oxide

4-Oxocyclophosphamide

2-<Bis(2-chlorethyl)amino>-4-oxo-tetrahydro-2H-1,3,2-oxazaphosphorin-2-oxid

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4H-1,3,2-Oxazaphosphorin-4-one,2-[bis(2-chloroethyl)amino]tetrahydro-, 2-oxide

Names

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Synthetic Route

Precursor & DownStream

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.