ALK/EGFR-IN-3

Modify Date: 2024-01-16 21:29:40

ALK/EGFR-IN-3 Structure
ALK/EGFR-IN-3 structure
 Common Name ALK/EGFR-IN-3
CAS Number 2730432-72-9 Molecular Weight 572.12
Density N/A Boiling Point N/A
Molecular Formula C27H34ClN7O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ALK/EGFR-IN-3


ALK/EGFR-IN-3 is a dual inhibitor of ALK and EGFR. ALK/EGFR-IN-3 inhibits the cell proliferation of H1975, PC9, and Baf3-EML4-ALK cancer cell lines with IC50s of 0.1360, 0.0332, and 0.0339 μM, respectively[1].

 Names

Name ALK/EGFR-IN-3

 ALK/EGFR-IN-3 Biological Activity

Description ALK/EGFR-IN-3 is a dual inhibitor of ALK and EGFR. ALK/EGFR-IN-3 inhibits the cell proliferation of H1975, PC9, and Baf3-EML4-ALK cancer cell lines with IC50s of 0.1360, 0.0332, and 0.0339 μM, respectively[1].
Related Catalog
References

[1]. An B, et al. Discovery of potent and effective inhibitors containing sulfoxide structures targeting EML4-ALK rearrangement and EGFR mutant non-small cell lung cancer. Bioorg Chem. 2023 Sep;138:106653.  

 Chemical & Physical Properties

Molecular Formula C27H34ClN7O3S
Molecular Weight 572.12
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