8-iso Prostaglandin E2

Modify Date: 2024-01-11 18:55:06

8-iso Prostaglandin E2 structure	Common Name	8-iso Prostaglandin E2
	CAS Number	27415-25-4	Molecular Weight	352.465
	Density	1.1±0.1 g/cm3	Boiling Point	530.1±50.0 °C at 760 mmHg
	Molecular Formula	C₂₀H₃₂O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	288.5±26.6 °C

Use of 8-iso Prostaglandin E2

8-Isoprostaglandin E2 (iPE2-III) is a member of the isoprostane class of prostanoids. 8-Isoprostaglandin E2 acts at the receptor for thromboxane A2 (the TP) in vivo to induce vasoconstriction and platelet aggregation. 8-Isoprostaglandin E2 enhances receptor-activated NFkappa B ligand (RANKL)-dependent osteoclastic potential of marrow hematopoietic precursors via the cAMP pathway[1][2].

Name	8-iso Prostaglandin E2
Synonym	More Synonyms

Description	8-Isoprostaglandin E2 (iPE2-III) is a member of the isoprostane class of prostanoids. 8-Isoprostaglandin E2 acts at the receptor for thromboxane A2 (the TP) in vivo to induce vasoconstriction and platelet aggregation. 8-Isoprostaglandin E2 enhances receptor-activated NFkappa B ligand (RANKL)-dependent osteoclastic potential of marrow hematopoietic precursors via the cAMP pathway[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor
References	[1]. Wilson SJ, et al. Heterodimerization of the alpha and beta isoforms of the human thromboxane receptor enhances isoprostane signaling. Biochem Biophys Res Commun. 2007;352(2):397-403. [2]. Tintut Y, et al. 8-Isoprostaglandin E2 enhances receptor-activated NFkappa B ligand (RANKL)-dependent osteoclastic potential of marrow hematopoietic precursors via the cAMP pathway. J Biol Chem. 2002;277(16):14221-14226.

Description

Related Catalog

Research Areas >> Cardiovascular Disease

Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor

References

[1]. Wilson SJ, et al. Heterodimerization of the alpha and beta isoforms of the human thromboxane receptor enhances isoprostane signaling. Biochem Biophys Res Commun. 2007;352(2):397-403.

[2]. Tintut Y, et al. 8-Isoprostaglandin E2 enhances receptor-activated NFkappa B ligand (RANKL)-dependent osteoclastic potential of marrow hematopoietic precursors via the cAMP pathway. J Biol Chem. 2002;277(16):14221-14226.

Density	1.1±0.1 g/cm3
Boiling Point	530.1±50.0 °C at 760 mmHg
Molecular Formula	C₂₀H₃₂O₅
Molecular Weight	352.465
Flash Point	288.5±26.6 °C
Exact Mass	352.224976
PSA	94.83000
LogP	1.88
Vapour Pressure	0.0±3.2 mmHg at 25°C
Index of Refraction	1.561

l-7-(3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-5-heptenoic acid

(5E,13E)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid

5-Heptenoic acid, 7-[3-hydroxy-2- (3-hydroxy-1-octenyl)-5-oxocyclopentyl]-

(5Z,8β,11α,12ξ,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid

5-Heptenoic acid, 7-(3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-

7-(3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-5-heptenoic acid

(5E)-7-{3-Hydroxy-2-[(1E)-3-hydroxy-1-octen-1-yl]-5-oxocyclopentyl}-5-heptenoic acid

Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-9-oxo-, (5Z,8β,11α,12ξ,13E,15S)-

5-Heptenoic acid, 7-(3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-, l-

Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-9-oxo-, (5E,13E)-

7-[3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl]-5-heptenoic acid

DC Chemicals Limited
China
Product Name: 8-Isoprostaglandin E2
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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8-iso Prostaglandin E2

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