18bioder

Modify Date: 2025-08-22 12:27:04

18bioder Structure
18bioder structure
Common Name 18bioder
CAS Number 275374-93-1 Molecular Weight 210.62
Density N/A Boiling Point N/A
Molecular Formula C9H7ClN2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 18bioder


18BIOder is a neuroprotective inhibitor of GSK-3β, highly selectively inhibiting HIV-1. It is the second generation derivative of 6BIO.

 Names

Name 18BIOder

 18bioder Biological Activity

Description 18BIOder is a neuroprotective inhibitor of GSK-3β, highly selectively inhibiting HIV-1. It is the second generation derivative of 6BIO.
References 1. Guendel I, Iordanskiy S, Van Duyne R, Kehn-Hall K, Saifuddin M, Das R, Jaworski E, Sampey GC, Senina S, Shultz L, Narayanan A, Chen H, Lepene B, Zeng C, Kashanchi F. Novel neuroprotective GSK-3β inhibitor restricts Tat-mediated HIV-1 replication. J Virol. 2014 Jan;88(2):1189-208. doi: 10.1128/JVI.01940-13. Epub 2013 Nov 13. PubMed PMID: 24227837; PubMed Central PMCID: PMC3911635.

 Chemical & Physical Properties

Molecular Formula C9H7ClN2O2
Molecular Weight 210.62
InChIKey KYJQVITTWJIVOJ-UHFFFAOYSA-N
SMILES Cc1c(Cl)ccc2c(N=O)c(O)[nH]c12
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