CCR8 antagonist 2

Modify Date: 2024-01-09 17:42:36

CCR8 antagonist 2 Structure
CCR8 antagonist 2 structure
Common Name CCR8 antagonist 2
CAS Number 2756350-98-6 Molecular Weight 464.02
Density N/A Boiling Point N/A
Molecular Formula C23H30ClN3O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CCR8 antagonist 2


CCR8 antagonist 2 is a potent antagonist of CCR8. CCR8 (C-C Motif Chemokine Receptor 8) is predominantly expressed on Treg cells and Th2 cells, but not on Th1 cells. CCR8 antagonist 2 inhibits CCR8 activity, which may be used in the treatment of diseases mediated by CCR8, such as cancer, and/or neuropathic pain (extracted from patent WO2022000443A1, compound 220)[1].

 Names

Name CCR8 antagonist 2

 CCR8 antagonist 2 Biological Activity

Description CCR8 antagonist 2 is a potent antagonist of CCR8. CCR8 (C-C Motif Chemokine Receptor 8) is predominantly expressed on Treg cells and Th2 cells, but not on Th1 cells. CCR8 antagonist 2 inhibits CCR8 activity, which may be used in the treatment of diseases mediated by CCR8, such as cancer, and/or neuropathic pain (extracted from patent WO2022000443A1, compound 220)[1].
Related Catalog
References

[1]. Guohuang FAN, et al. Methods and compositions for targeting tregs using ccr8 inhibitors.

 Chemical & Physical Properties

Molecular Formula C23H30ClN3O3S
Molecular Weight 464.02