DBCO-PEG24-acid

Modify Date: 2024-01-02 15:55:57

DBCO-PEG24-acid Structure
DBCO-PEG24-acid structure
Common Name DBCO-PEG24-acid
CAS Number 2765066-36-0 Molecular Weight 1433.67
Density N/A Boiling Point N/A
Molecular Formula C70H116N2O28 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DBCO-PEG24-acid


DBCO-PEG24-acid is a click chemistry reagent. DBCO-PEG24-acid is an analog of DBCO-Acid with PEG linker and a DBCO group. The DBCO groups is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. The hydrophilic PEG chain allows for increased water solubility. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research use only[1].

 Names

Name DBCO-PEG24-acid

 DBCO-PEG24-acid Biological Activity

Description DBCO-PEG24-acid is a click chemistry reagent. DBCO-PEG24-acid is an analog of DBCO-Acid with PEG linker and a DBCO group. The DBCO groups is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. The hydrophilic PEG chain allows for increased water solubility. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research use only[1].
Related Catalog
References

[1]. Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14(8):779-789.  

 Chemical & Physical Properties

Molecular Formula C70H116N2O28
Molecular Weight 1433.67