RMC-7977
Modify Date: 2025-08-25 18:10:23
RMC-7977 structure
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Common Name | RMC-7977 | ||
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| CAS Number | 2765082-12-8 | Molecular Weight | 865.09 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C47H60N8O6S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of RMC-7977RMC-7977 is a reversible, tri-complex RAS inhibitor with broad spectrum activity for both mutant and wild-type (WT) KRAS, NRAS, and HRAS variants.RMC-7977 can lead to tumor regressions and was well tolerated in diverse RAS-addicted preclinical cancer models. RMC-7977 also can inhibit the growth of KRASG12C cancer models[1]. |
| Name | RMC-7977 |
|---|
| Description | RMC-7977 is a reversible, tri-complex RAS inhibitor with broad spectrum activity for both mutant and wild-type (WT) KRAS, NRAS, and HRAS variants.RMC-7977 can lead to tumor regressions and was well tolerated in diverse RAS-addicted preclinical cancer models. RMC-7977 also can inhibit the growth of KRASG12C cancer models[1]. |
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| References |
| Molecular Formula | C47H60N8O6S |
|---|---|
| Molecular Weight | 865.09 |
| InChIKey | NBLZKEHVVJSAAY-UDSCPAMHSA-N |
| SMILES | CCn1c(-c2cc(N3CCN(C4CC4)CC3)cnc2C(C)OC)c2c3cc(ccc31)-c1csc(n1)CC(NC(=O)C1C3COCC31)C(=O)N1CCCC(N1)C(=O)OCC(C)(C)C2 |