4-(N-ETHYL-N-4-HYDROXYBUTYL)AMINO-2,5,6-TRIMETHYL-7-(2,4,6-TRIMETHYLPHENYL)PYRROLO[2,3-D]PYRIMIDINE HYDROCHLORIDE structure
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Common Name | 4-(N-ETHYL-N-4-HYDROXYBUTYL)AMINO-2,5,6-TRIMETHYL-7-(2,4,6-TRIMETHYLPHENYL)PYRROLO[2,3-D]PYRIMIDINE HYDROCHLORIDE | ||
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CAS Number | 276890-57-4 | Molecular Weight | 431.01400 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C24H35ClN4O | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | N/A |
Name | 4-[ethyl-[2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)pyrrolo[2,3-d]pyrimidin-4-yl]amino]butan-1-ol,hydrochloride |
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Synonym | More Synonyms |
Molecular Formula | C24H35ClN4O |
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Molecular Weight | 431.01400 |
Exact Mass | 430.25000 |
PSA | 54.18000 |
LogP | 5.67170 |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
~77% 4-(N-ETHYL-N-4-... CAS#:276890-57-4 |
Literature: Hiebel, Anne-Cecile; Partilla, John S.; Rothman, Richard B.; Jacobson, Arthur E.; Rice, Kenner C. Journal of Labelled Compounds and Radiopharmaceuticals, 2006 , vol. 49, # 7 p. 635 - 640 |
~% 4-(N-ETHYL-N-4-... CAS#:276890-57-4 |
Literature: Hsin, Ling-Wei; Webster, Elizabeth L.; Chrousos, George P.; Gold, Philip W.; Eckelman, William C.; Contoreggi, Carlo; Rice, Kenner C. Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 8 p. 707 - 710 |
Precursor 2 | |
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DownStream 0 |
CRHR1 Receptor binding and lipophilicity of pyrrolopyrimidines, potential nonpeptide corticotropin-releasing hormone type 1 receptor antagonists.
Bioorg. Med. Chem. 10 , 175-183, (2002) A series of compounds related to N-butyl-N-ethyl[2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)pyrrolo[2,3-d]pyrimidin-4-yl]amine (1, antalarmin) have been prepared and evaluated for their CRHR1 binding af... |
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Ethanol augments GABAergic transmission in the central amygdala via CRF1 receptors.
Science 303 , 1512-1514, (2004) The central amygdala (CeA) plays a role in the relationship among stress, corticotropin-releasing factor (CRF), and alcohol abuse. In whole-cell recordings, both CRF and ethanol enhanced gamma-aminobu... |
4-(N-Ethyl-n-4-hydroxybutyl)amino-2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)pyrrolo[2,3-d]pyrimidine hydrochloride |
4-[ethyll[2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)pyrrolo[2,3-d]pyrimidin-4-yl]amino]butan-1-ol |
LWH-63 hydrochloride |
NIH-3 |
4-[ethyl[2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)pyrrolo[2,3-d]pyrimidin-4-yl]amino]butan-1-ol |