(2S,4R)-1-[(2S)-2-(4-cyclopropyltriazol-1-yl)-3,3-dimethylbutanoyl]-4-hydroxy-N-[(5S)-2-(4-methyl-1,3-thiazol-5-yl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-yl]pyrrolidine-2-carboxamide

Modify Date: 2026-02-19 15:16:07

(2S,4R)-1-[(2S)-2-(4-cyclopropyltriazol-1-yl)-3,3-dimethylbutanoyl]-4-hydroxy-N-[(5S)-2-(4-methyl-1,3-thiazol-5-yl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-yl]pyrrolidine-2-carboxamide Structure
(2S,4R)-1-[(2S)-2-(4-cyclopropyltriazol-1-yl)-3,3-dimethylbutanoyl]-4-hydroxy-N-[(5S)-2-(4-methyl-1,3-thiazol-5-yl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-yl]pyrrolidine-2-carboxamide structure
Common Name (2S,4R)-1-[(2S)-2-(4-cyclopropyltriazol-1-yl)-3,3-dimethylbutanoyl]-4-hydroxy-N-[(5S)-2-(4-methyl-1,3-thiazol-5-yl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-yl]pyrrolidine-2-carboxamide
CAS Number 2771069-76-0 Molecular Weight 576.8
Density N/A Boiling Point N/A
Molecular Formula C31H40N6O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name (2S,4R)-1-[(2S)-2-(4-cyclopropyltriazol-1-yl)-3,3-dimethylbutanoyl]-4-hydroxy-N-[(5S)-2-(4-methyl-1,3-thiazol-5-yl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-yl]pyrrolidine-2-carboxamide

 Chemical & Physical Properties

Molecular Formula C31H40N6O3S
Molecular Weight 576.8
InChIKey IAVGSVXQQSNQFO-PWKYGKGFSA-N
SMILES CC1=C(SC=N1)C2=CC3=C(C=C2)[C@H](CCCC3)NC(=O)[C@@H]4C[C@H](CN4C(=O)[C@H](C(C)(C)C)N5C=C(N=N5)C6CC6)O

 Bioassay

View more

Name: Oral absorption in female C57Bl/6 mouse at 10 mg/kg measured upto 8 hrs by LC-MS/MS a...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5511968
Name: Oral bioavailability in female C57Bl/6 mouse at 10 mg/kg measured upto 8 hrs by LC-MS...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5511967
Name: Half life in female C57Bl/6 mouse at 10 mg/kg, po measured upto 8 hrs by LC-MS/MS ana...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5511966
Name: Volume of distribution in female C57Bl/6 mouse at 1 mg/kg, iv measured upto 8 hrs by ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5511965
Name: Plasma clearance in female C57Bl/6 mouse at 1 mg/kg, iv measured upto 8 hrs by LC-MS/...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5511964
Name: Plasma protein binding in CD-1 mouse at 5 uM incubated for 4 hrs by HPLC analysis
Source: ChEMBL
Target: N/A
External Id: CHEMBL5511962
Name: Plasma protein binding in human at 5 uM incubated for 4 hrs by HPLC analysis
Source: ChEMBL
Target: N/A
External Id: CHEMBL5511961
Name: Apparent permeability from apical to basolateral side in MDCKI cells at 10 uM measure...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5511960
Name: Binding affinity to VHL (unknown origin)-NanoLuc fusion protein expressed in HEK293 c...
Source: ChEMBL
Target: von Hippel-Lindau disease tumor suppressor
External Id: CHEMBL5511957
Name: Binding affinity to VHL (unknown origin)-NanoLuc fusion protein expressed in HEK293 c...
Source: ChEMBL
Target: von Hippel-Lindau disease tumor suppressor
External Id: CHEMBL5511956
Total 10, Current Page 1 of 1
1
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.