PROTAC α-synuclein degrader 5

Modify Date: 2024-04-03 12:50:22

PROTAC α-synuclein degrader 5 structure	Common Name	PROTAC α-synuclein degrader 5
	CAS Number	2781922-42-5	Molecular Weight	767.78
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₉H₄₁N₇O₁₀	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PROTAC α-synuclein degrader 5

PROTAC α-synuclein degrader 5 is a highly selective small-molecule degraders (PROTAC) of α-synuclein aggregates, with an DC50 of 7.51 μM and the highest degradation rate Dmax of 89%. PROTAC α-synuclein degrader 5 contains probe molecule sery308 and E3 ligase ligands. PROTAC α-synuclein degrader 5 can be used for neurological disease research[1].

Name	PROTAC α-synuclein degrader 5

Description	PROTAC α-synuclein degrader 5 is a highly selective small-molecule degraders (PROTAC) of α-synuclein aggregates, with an DC50 of 7.51 μM and the highest degradation rate Dmax of 89%. PROTAC α-synuclein degrader 5 contains probe molecule sery308 and E3 ligase ligands. PROTAC α-synuclein degrader 5 can be used for neurological disease research[1].
Related Catalog	Signaling Pathways >> PROTAC >> PROTAC Research Areas >> Neurological Disease
References	[1]. Yichen Tong, et.al. Discovery of Small-Molecule Degraders for Alpha-Synuclein Aggregates. Journal of Medicinal Chemistry 2023 66 (12), 7926-7942

Molecular Formula	C₃₉H₄₁N₇O₁₀
Molecular Weight	767.78
InChIKey	IYFKRANQUJUTKF-UHFFFAOYSA-N
SMILES	O=C(CNc1cccc(-c2cc(-c3ccc4c(c3)OCO4)[nH]n2)c1)NCCOCCOCCOCCNc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O

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PROTAC α-synuclein degrader 5

Use of PROTAC α-synuclein degrader 5

Names

PROTAC α-synuclein degrader 5 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.