RTIOXA-43

Modify Date: 2025-08-25 15:39:15

RTIOXA-43 Structure
RTIOXA-43 structure
Common Name RTIOXA-43
CAS Number 2832067-72-6 Molecular Weight 663.79
Density N/A Boiling Point N/A
Molecular Formula C37H37N5O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of RTIOXA-43


RTIOXA-43 is a orexin receptor agonist with EC50s of 24 nM and 24 nM for OX2 and OX1 receptors, respectively[1].

 Names

Name RTIOXA-43

 RTIOXA-43 Biological Activity

Description RTIOXA-43 is a orexin receptor agonist with EC50s of 24 nM and 24 nM for OX2 and OX1 receptors, respectively[1].
Related Catalog
Target

OX1:24 nM (EC50)

OX2:24 nM (EC50)

References

[1]. Yanan Zhang, et al. Arylsulfoxamides as orexin receptor agonists. WO2022187231A1.

[2]. Kotz, Catherine, et al. Small Molecule Orexin Agonists Enhance Physical Activity, Cognition and Sleep Quality in Aged Mice. Obesity; Silver Spring Vol. 29, (Dec 2021): 163.

 Chemical & Physical Properties

Molecular Formula C37H37N5O5S
Molecular Weight 663.79
InChIKey WIANBLHLJZGLLG-UHFFFAOYSA-N
SMILES COc1ccc(-c2cccc(C(=O)N(C)Cc3ccncc3)c2)cc1S(=O)(=O)Nc1cccc(NCCNC(=O)c2cccc(C)c2)c1
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.