RTIOXA-43

Modify Date: 2024-01-06 22:27:12

RTIOXA-43 Structure
RTIOXA-43 structure
Common Name RTIOXA-43
CAS Number 2832067-72-6 Molecular Weight 663.79
Density N/A Boiling Point N/A
Molecular Formula C37H37N5O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of RTIOXA-43


RTIOXA-43 is a orexin receptor agonist with EC50s of 24 nM and 24 nM for OX2 and OX1 receptors, respectively[1].

 Names

Name RTIOXA-43

 RTIOXA-43 Biological Activity

Description RTIOXA-43 is a orexin receptor agonist with EC50s of 24 nM and 24 nM for OX2 and OX1 receptors, respectively[1].
Related Catalog
Target

OX1:24 nM (EC50)

OX2:24 nM (EC50)

References

[1]. Yanan Zhang, et al. Arylsulfoxamides as orexin receptor agonists. WO2022187231A1.

[2]. Kotz, Catherine, et al. Small Molecule Orexin Agonists Enhance Physical Activity, Cognition and Sleep Quality in Aged Mice. Obesity; Silver Spring Vol. 29, (Dec 2021): 163.

 Chemical & Physical Properties

Molecular Formula C37H37N5O5S
Molecular Weight 663.79
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