Anti-infective agent 6

Modify Date: 2024-04-06 17:44:51

Anti-infective agent 6 Structure
Anti-infective agent 6 structure
Common Name Anti-infective agent 6
CAS Number 2839192-35-5 Molecular Weight 257.28
Density N/A Boiling Point N/A
Molecular Formula C15H15NO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Anti-infective agent 6


Anti-infective agent 6 (compound 28) is a potent anti-infectious agent. Anti-infective agent 6 shows a good activity against P. falciparum F32-ART (IC50=1.4 μM) with a good selectivity index (SI>36). Anti-infective agent 6 also shows a potency against L. donovani (IC50=3.5 μM)[1].

 Names

Name Anti-infective agent 6

 Anti-infective agent 6 Biological Activity

Description Anti-infective agent 6 (compound 28) is a potent anti-infectious agent. Anti-infective agent 6 shows a good activity against P. falciparum F32-ART (IC50=1.4 μM) with a good selectivity index (SI>36). Anti-infective agent 6 also shows a potency against L. donovani (IC50=3.5 μM)[1].
Related Catalog
In Vitro Anti-infective agent 6 (compound 28) is less cytotoxic with a CC50 value higher than 100 μM in macrophage RAW 264.7 cells and consequently a SI higher than 28 for Leishmania parasites[1].
References

[1]. Koumpoura CL, et al. Design of Anti-infectious Agents from Lawsone in a Three-Component Reaction with Aldehydes and Isocyanides. ACS Omega. 2022 Oct 3;7(40):35635-35655.

 Chemical & Physical Properties

Molecular Formula C15H15NO3
Molecular Weight 257.28