TH-Z816

Modify Date: 2025-11-30 22:46:05

TH-Z816 Structure
TH-Z816 structure
Common Name TH-Z816
CAS Number 2847881-42-7 Molecular Weight 486.65
Density N/A Boiling Point N/A
Molecular Formula C29H38N6O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TH-Z816


TH-Z816 is a reversible inhibitor againstKRAS(G12D)mutation with an IC50 value of 14 μM, which can be used in cancer research[1].

 Names

Name TH-Z816

 TH-Z816 Biological Activity

Description TH-Z816 is a reversible inhibitor againstKRAS(G12D)mutation with an IC50 value of 14 μM, which can be used in cancer research[1].
Related Catalog
References

[1]. Zhongwei Mao, et al. KRAS(G12D) can be targeted by potent inhibitors via formation of salt bridge. Cell Discov. 2022 Jan 25;8(1):5.  

 Chemical & Physical Properties

Molecular Formula C29H38N6O
Molecular Weight 486.65
InChIKey UAZYYGRPOMNMMP-GGAORHGYSA-N
SMILES Cc1cccc2cccc(N3CCc4c(nc(OCC5CCCN5C)nc4N4CCNCC4C)C3)c12
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