Epoxylathyrol

Modify Date: 2025-08-25 10:02:57

Epoxylathyrol structure	Common Name	Epoxylathyrol
	CAS Number	28649-60-7	Molecular Weight	350.449
	Density	1.3±0.1 g/cm3	Boiling Point	542.3±50.0 °C at 760 mmHg
	Molecular Formula	C₂₀H₃₀O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	190.9±23.6 °C

Use of Epoxylathyrol

Epoxylathyrol, an epoxylathyrane derivative isolated from the Euphorbia boetica, is a P-glycoprotein (P-gp) inhibitor. Epoxylathyrol is a P-gp-mediated multidrug resistance (MDR) reverser[1][2].

Name	6,20-Epoxylathyrol
Synonym	More Synonyms

Description	Epoxylathyrol, an epoxylathyrane derivative isolated from the Euphorbia boetica, is a P-glycoprotein (P-gp) inhibitor. Epoxylathyrol is a P-gp-mediated multidrug resistance (MDR) reverser[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Membrane Transporter/Ion Channel >> P-glycoprotein
In Vitro	Epoxylathyrol has no significant antiproliferative activity in EPG85-257P (parental; IC50>100 uM), EPG85-257RNOV (multidrug resistance [MDR] phenotype; IC50>100 uM), and EPG85-257RDB (multidrug resistance [MDR] phenotype; IC50=70.53 uM)[1].
References	[1]. Mariana Alves Reis, et al. Epoxylathyrane Derivatives as MDR-Selective Compounds for Disabling Multidrug Resistance in Cancer. Front Pharmacol. 2020 May 8;11:599. [2]. Wei Jiao, et al. Lathyrane diterpenes from Euphorbia lathyris as modulators of multidrug resistance and their crystal structures. Bioorg Med Chem. 2009 Jul 1;17(13):4786-92.

Density	1.3±0.1 g/cm3
Boiling Point	542.3±50.0 °C at 760 mmHg
Molecular Formula	C₂₀H₃₀O₅
Molecular Weight	350.449
Flash Point	190.9±23.6 °C
Exact Mass	350.209320
PSA	90.29000
LogP	1.62
Vapour Pressure	0.0±3.3 mmHg at 25°C
Index of Refraction	1.586
InChIKey	VEFQDSXSELSHMX-QVTWHFOYSA-N
SMILES	CC1=CC2C(CCC3(CO3)C(O)C3C(O)C(C)CC3(O)C1=O)C2(C)C
Storage condition	2-8C

Epoxylathyrol

Spiro[9H-cyclopenta[a]cyclopropa[f]cycloundecene-9,2'-oxiran]-4(1H)-one, 1a,4a,5,6,7,7a,8,10,11,11a-decahydro-4a,7,8-trihydroxy-1,1,3,6-tetramethyl-, (1aR,2Z,4aR,6S,7S,7aR,8S,9R,11aS)-

Spiro[9H-cyclopenta[a]cyclopropa[f]cycloundecene-9,2'-oxiran]-4(1H)-one, 1a,4a,5,6,7,7a,8,10,11,11a-decahydro-4a,7,8-trihydroxy-1,1,3,6-tetramethyl-, (1aR,2E,4aR,6S,7S,7aR,8S,9R,11aS)-

(1aR,2Z,4aR,6S,7S,7aR,8S,9R,11aS)-4a,7,8-Trihydroxy-1,1,3,6-tetramethyl-1a,4a,5,6,7,7a,8,10,11,11a-decahydrospiro[cyclopenta[a]cyclopropa[f][11]annulene-9,2'-oxiran]-4(1H)-one

(1aR,2E,4aR,6S,7S,7aR,8S,9R,11aS)-4a,7,8-Trihydroxy-1,1,3,6-tetramethyl-1a,4a,5,6,7,7a,8,10,11,11a-decahydrospiro[cyclopenta[a]cyclopropa[f][11]annulene-9,2'-oxiran]-4(1H)-one

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Epoxylathyrol
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Epoxylathyrol
Price: ￥1478.0/20mg
Purity: 98.0%
Delivery: 2 Day
Contact: Liu jia
Email: 2130147988@qq.com

DC Chemicals Limited
China
Product Name: Epoxylathyrol
Price: $280.0/20mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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Epoxylathyrol

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.