m-PEG12-2-methylacrylate

Modify Date: 2024-04-09 20:21:00

m-PEG12-2-methylacrylate Structure
m-PEG12-2-methylacrylate structure
Common Name m-PEG12-2-methylacrylate
CAS Number 2867-46-1 Molecular Weight 628.75
Density N/A Boiling Point N/A
Molecular Formula C29H56O14 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG12-2-methylacrylate


Propargyl-PEG13-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Propargyl-PEG13-alcohol

 m-PEG12-2-methylacrylate Biological Activity

Description Propargyl-PEG13-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C29H56O14
Molecular Weight 628.75
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