1H-Indole-2-carboxamide,5-methoxy-N,N-dimethyl-

Modify Date: 2024-01-02 02:14:31

1H-Indole-2-carboxamide,5-methoxy-N,N-dimethyl- Structure
1H-Indole-2-carboxamide,5-methoxy-N,N-dimethyl- structure
Common Name 1H-Indole-2-carboxamide,5-methoxy-N,N-dimethyl-
CAS Number 28837-74-3 Molecular Weight 218.25200
Density 1.204g/cm3 Boiling Point 429.8ºC at 760mmHg
Molecular Formula C12H14N2O2 Melting Point N/A
MSDS N/A Flash Point 213.8ºC

 Names

Name 5-methoxy-N,N-dimethyl-1H-indole-2-carboxamide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.204g/cm3
Boiling Point 429.8ºC at 760mmHg
Molecular Formula C12H14N2O2
Molecular Weight 218.25200
Flash Point 213.8ºC
Exact Mass 218.10600
PSA 45.33000
LogP 1.87830
Vapour Pressure 1.36E-07mmHg at 25°C
Index of Refraction 1.619

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NL5994488
CHEMICAL NAME :
Indole-2-carboxamide, N,N-dimethyl-5-methoxy-
CAS REGISTRY NUMBER :
28837-74-3
BEILSTEIN REFERENCE NO. :
0398307
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C12-H14-N2-O2
MOLECULAR WEIGHT :
218.28

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IJOCAP Indian Journal of Chemistry. (New Delhi, India) V.1-13, 1963-75. Divided into Indian Journal of Chemistry, Section A and Indian Journal of Chemistry, Section B. Volume(issue)/page/year: 8,704,1970

 Synthetic Route

~76%

1H-Indole-2-carboxamide,5-methoxy-N,N-dimethyl- Structure

1H-Indole-2-car...

CAS#:28837-74-3

Literature: WYETH LLC; AYRAL-KALOUSTIAN, Semiramis; MANSOUR, Tarek Suhayl; TSOU, Hwei-Ru; ZHANG, Nan; VENKATESAN, Aranapakam M.; DI, Li; KERNS, Edward H. Patent: WO2010/30727 A1, 2010 ; Location in patent: Page/Page column 99-100 ; WO 2010/030727 A1

~%

1H-Indole-2-carboxamide,5-methoxy-N,N-dimethyl- Structure

1H-Indole-2-car...

CAS#:28837-74-3

Literature: Pelaprat, Didier; Oberlin, Robert; Le Guen, Irene; Roques, Bernard P.; Pecq, Jean-Bernard Le Journal of Medicinal Chemistry, 1980 , vol. 23, # 12 p. 1330 - 1335

~%

1H-Indole-2-carboxamide,5-methoxy-N,N-dimethyl- Structure

1H-Indole-2-car...

CAS#:28837-74-3

Literature: Pelaprat, Didier; Oberlin, Robert; Le Guen, Irene; Roques, Bernard P.; Pecq, Jean-Bernard Le Journal of Medicinal Chemistry, 1980 , vol. 23, # 12 p. 1330 - 1335

 Synonyms

N,N-Dimethyl-5-methoxyindole-2-carboxamide
Indole-2-carboxamide,N,N-dimethyl-5-methoxy
5-methoxy-indole-2-carboxylic acid dimethylamide
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