DGKα-IN-8

Modify Date: 2024-04-07 16:50:54

DGKα-IN-8 Structure
DGKα-IN-8 structure
Common Name DGKα-IN-8
CAS Number 2886717-70-8 Molecular Weight 473.88
Density N/A Boiling Point N/A
Molecular Formula C23H19ClF3N5O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DGKα-IN-8


DGKα-IN-8 (Example 51) is a DGKα inhibitor (IC50=22.491 nM; EC50=0.256 nM). DGKα-IN-8 can be used to study cancer, including solid tumors, and viral infections, such as HIV or hepatitis B virus infection[1].

 Names

Name DGKα-IN-8

 DGKα-IN-8 Biological Activity

Description DGKα-IN-8 (Example 51) is a DGKα inhibitor (IC50=22.491 nM; EC50=0.256 nM). DGKα-IN-8 can be used to study cancer, including solid tumors, and viral infections, such as HIV or hepatitis B virus infection[1].
Related Catalog
Target

IC50: 22.491 nM (DGKα)[1].

References

[1]. Julian A Codelli, et al. Diacylglyercol kinase modulating compounds. Patent WO2022271659A1.

 Chemical & Physical Properties

Molecular Formula C23H19ClF3N5O
Molecular Weight 473.88
InChIKey AZQWRUDQALWXQL-UHFFFAOYSA-N
SMILES Cn1nnc2nc(N(CC(F)F)c3cc(F)cc(C#CC(C)(C)O)c3)c3ccc(Cl)cc3c21
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