Galectin-3 antagonist 1

Modify Date: 2025-08-24 22:24:49

Galectin-3 antagonist 1 Structure
Galectin-3 antagonist 1 structure
 Common Name Galectin-3 antagonist 1
CAS Number 2921603-03-2 Molecular Weight 495.86
Density N/A Boiling Point N/A
Molecular Formula C22H22ClNO10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Galectin-3 antagonist 1


Galectin-3 antagonist 1 (compound 15) is a potent and selective Galectin-3 (Gal-3) antagonist with Kd value of 5.3 μM. Meanwhile, Galectin-3 antagonist 1 binds to various Galectin with Kd values of 250 μM (Gal-4N), 18 μM (Gal-4C), 450 μM (Gal-8C), respectively[1].

 Names

Name Galectin-3 antagonist 1

 Galectin-3 antagonist 1 Biological Activity

Description Galectin-3 antagonist 1 (compound 15) is a potent and selective Galectin-3 (Gal-3) antagonist with Kd value of 5.3 μM. Meanwhile, Galectin-3 antagonist 1 binds to various Galectin with Kd values of 250 μM (Gal-4N), 18 μM (Gal-4C), 450 μM (Gal-8C), respectively[1].
Related Catalog
Target

Kd: 5.3 μM (Gal-3), 250 μM (Gal-4N), 18 μM (Gal-4C), 450 μM (Gal-8C)[1]

References

[1]. Bum-Erdene K, et al. Novel Selective Galectin-3 Antagonists Are Cytotoxic to Acute Lymphoblastic Leukemia. J Med Chem. 2022 Apr 28;65(8):5975-5989.  

 Chemical & Physical Properties

Molecular Formula C22H22ClNO10
Molecular Weight 495.86
InChIKey FSBFERQGFVBNEJ-NOYKIMNZSA-N
SMILES COC1OC(CO)C(O)C(OC(=O)c2ccc(C)cc2)C1OC(=O)c1ccc(Cl)cc1[N+](=O)[O-]
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Chemsrc provides Galectin-3 antagonist 1(CAS#:2921603-03-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Galectin-3 antagonist 1 are included as well.>> amp version: Galectin-3 antagonist 1

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