BI-2865
Modify Date: 2025-09-18 16:20:28
BI-2865 structure
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Common Name | BI-2865 | ||
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| CAS Number | 2937327-93-8 | Molecular Weight | 465.57 | |
| Density | 1.38±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | Boiling Point | 708.7±70.0 °C(Predicted) | |
| Molecular Formula | C23H27N7O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BI-2865BI-2865 is a none-covalent pan-KRAS Inhibitor. BI-2865 binds to WT, G12C, G12D, G12V and G13D mutant KRAS with KDs of 6.9, 4.5, 32, 26, 4.3 nM respectively. BI-2865 inhibits the proliferation of G12C, G12D or G12V mutant KRAS expressing BaF3 cells (mean IC50: roughly 140 nM)[1]. |
| Name | BI-2865 |
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| Description | BI-2865 is a none-covalent pan-KRAS Inhibitor. BI-2865 binds to WT, G12C, G12D, G12V and G13D mutant KRAS with KDs of 6.9, 4.5, 32, 26, 4.3 nM respectively. BI-2865 inhibits the proliferation of G12C, G12D or G12V mutant KRAS expressing BaF3 cells (mean IC50: roughly 140 nM)[1]. |
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| Related Catalog | |
| References |
| Density | 1.38±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) |
|---|---|
| Boiling Point | 708.7±70.0 °C(Predicted) |
| Molecular Formula | C23H27N7O2S |
| Molecular Weight | 465.57 |