AChE-IN-30

Modify Date: 2024-01-27 18:19:58

AChE-IN-30 Structure
AChE-IN-30 structure
Common Name AChE-IN-30
CAS Number 2937454-22-1 Molecular Weight 376.45
Density N/A Boiling Point N/A
Molecular Formula C22H24N4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AChE-IN-30


AChE-IN-30 is an AChE inhibitor with an IC50 value of 4.4 μM. AChE-IN-30 has neuroprotective activity, and inhibits H2O2-induced apoptosis by suppressing intracellular ROS accumulation. AChE-IN-30 can be used for research of Alzheimer's disease[1].

 Names

Name AChE-IN-30

 AChE-IN-30 Biological Activity

Description AChE-IN-30 is an AChE inhibitor with an IC50 value of 4.4 μM. AChE-IN-30 has neuroprotective activity, and inhibits H2O2-induced apoptosis by suppressing intracellular ROS accumulation. AChE-IN-30 can be used for research of Alzheimer's disease[1].
Related Catalog
References

[1]. Wan D, et al. Design, Synthesis, and Biological Activity of Donepezil: Aromatic Amine Hybrids as Anti-Alzheimerss Drugs. ACS Omega. 2023 Jun 5;8(24):21802-21812.  

 Chemical & Physical Properties

Molecular Formula C22H24N4O2
Molecular Weight 376.45
InChIKey RMNHWEFBTVCRRS-UHFFFAOYSA-N
SMILES Nc1ccc(Nc2c(NC3CCN(Cc4ccccc4)CC3)c(=O)c2=O)cc1
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