(1S,9R)-Exatecan mesylate

Modify Date: 2024-03-10 18:59:05

(1S,9R)-Exatecan mesylate structure	Common Name	(1S,9R)-Exatecan mesylate
	CAS Number	2938875-54-6	Molecular Weight	531.55
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₂₆FN₃O₇S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (1S,9R)-Exatecan mesylate

(1S,9R)-Exatecan mesylate ((1S,9R)-DX8951f) is an isomer of Exatecan mesylate (HY-13631A). Exatecan mesylate (DX8951f) is an inhibitor of DNA topoisomerase I with an IC50 of 2.2 μM (0.975 μg/mL) and can be used in cancer research[1].

Name	(1S,9R)-Exatecan mesylate

Description	(1S,9R)-Exatecan mesylate ((1S,9R)-DX8951f) is an isomer of Exatecan mesylate (HY-13631A). Exatecan mesylate (DX8951f) is an inhibitor of DNA topoisomerase I with an IC50 of 2.2 μM (0.975 μg/mL) and can be used in cancer research[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase
References	[1]. Mitsui I, et al. A new water-soluble camptothecin derivative, DX-8951f, exhibits potent antitumor activity against human tumors in vitro and in vivo. Jpn J Cancer Res. 1995 Aug;86(8):776-82.

Molecular Formula	C₂₅H₂₆FN₃O₇S
Molecular Weight	531.55

(1S,9R)-Exatecan mesylate

Use of (1S,9R)-Exatecan mesylate

Names

(1S,9R)-Exatecan mesylate Biological Activity

Chemical & Physical Properties