HIV-1 inhibitor-56

Modify Date: 2025-08-26 19:18:38

HIV-1 inhibitor-56 Structure
HIV-1 inhibitor-56 structure
Common Name HIV-1 inhibitor-56
CAS Number 2952530-45-7 Molecular Weight 475.91
Density N/A Boiling Point N/A
Molecular Formula C22H14ClN7O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HIV-1 inhibitor-56


HIV-1 inhibitor-56 (compound 12126065) is a potent HIV-1 non-nucleoside reverse transcriptase inhibitor. HIV-1 inhibitor-56 has antiviral activity against wild-type HIV-1 in TZM cells with an EC50 value of 0.24 nM. HIV-1 inhibitor-56 penetrates the blood-brain barrier[1].

 Names

Name HIV-1 inhibitor-56

 HIV-1 inhibitor-56 Biological Activity

Description HIV-1 inhibitor-56 (compound 12126065) is a potent HIV-1 non-nucleoside reverse transcriptase inhibitor. HIV-1 inhibitor-56 has antiviral activity against wild-type HIV-1 in TZM cells with an EC50 value of 0.24 nM. HIV-1 inhibitor-56 penetrates the blood-brain barrier[1].
Related Catalog
References

[1]. Lane T, et, al. N-Phenyl-1-(phenylsulfonyl)-1H-1,2,4-triazol-3-amine as a New Class of HIV-1 Non-nucleoside Reverse Transcriptase Inhibitor. J Med Chem. 2023 May 11;66(9):6193-6217.  

 Chemical & Physical Properties

Molecular Formula C22H14ClN7O2S
Molecular Weight 475.91
InChIKey RXXGEBPXQBMTIJ-NSCUHMNNSA-N
SMILES N#CC=Cc1ccc2c(S(=O)(=O)n3nc(Nc4ccc(C#N)c(Cl)c4)nc3N)cccc2c1
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