4-CPPC

Modify Date: 2024-01-24 10:26:32

4-CPPC Structure
4-CPPC structure
Common Name 4-CPPC
CAS Number 29553-70-6 Molecular Weight 287.224
Density 1.5±0.1 g/cm3 Boiling Point 595.2±50.0 °C at 760 mmHg
Molecular Formula C14H9NO6 Melting Point N/A
MSDS N/A Flash Point 313.8±30.1 °C

 Use of 4-CPPC


4-CPPC is the first reversible and selective inhibitor of pro-inflammatory protein macrophage migration inhibitory factor-2 (MIF-2) with Ki of 33 uM, 13-fold selectivity for human MIF-2 versus human MIF-1.

 Names

Name 4-(3-Carboxyphenyl)-2,5-pyridinedicarboxylic acid
Synonym More Synonyms

 4-CPPC Biological Activity

Description 4-CPPC is the first reversible and selective inhibitor of pro-inflammatory protein macrophage migration inhibitory factor-2 (MIF-2) with Ki of 33 uM, 13-fold selectivity for human MIF-2 versus human MIF-1.
References References 1. Pantouris G, et al. Biochemistry. 2018 Jun 12. doi: 10.1021/acs.biochem.8b00344. View Related Products by Target Other Targets

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 595.2±50.0 °C at 760 mmHg
Molecular Formula C14H9NO6
Molecular Weight 287.224
Flash Point 313.8±30.1 °C
Exact Mass 287.042999
LogP 1.01
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.675

 Synonyms

4-(3-Carboxyphenyl)-2,5-pyridinedicarboxylic acid
2,5-Pyridinedicarboxylic acid, 4-(3-carboxyphenyl)-