RFRP-1(human)

Modify Date: 2024-01-09 15:03:41

RFRP-1(human) Structure
RFRP-1(human) structure
Common Name RFRP-1(human)
CAS Number 311309-25-8 Molecular Weight 1428.70000
Density N/A Boiling Point N/A
Molecular Formula C67H101N19O14S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of RFRP-1(human)


RFRP-1(human) is a potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). Attenuates contractile function of isolated rat and rabbit cardiac myocytes. Reduces heart rate, stroke volume, ejection fraction and cardiac output, and increases plasma prolactin levels in rats.

 Names

Name MPHSFANLPLRF-amide
Synonym More Synonyms

 RFRP-1(human) Biological Activity

Description RFRP-1(human) is a potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). Attenuates contractile function of isolated rat and rabbit cardiac myocytes. Reduces heart rate, stroke volume, ejection fraction and cardiac output, and increases plasma prolactin levels in rats.
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 Chemical & Physical Properties

Molecular Formula C67H101N19O14S
Molecular Weight 1428.70000
Exact Mass 1427.75000
PSA 550.83000
LogP 3.27730

 Synonyms

hRFRP-1
human RFamide-related peptide-1
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