Orotidine
Orotidine structure
|
Common Name | Orotidine | ||
|---|---|---|---|---|
| CAS Number | 314-50-1 | Molecular Weight | 288.211 | |
| Density | 1.8±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C10H12N2O8 | Melting Point | 200ºC | |
| MSDS | USA | Flash Point | N/A | |
Use of OrotidineOrotidine is an intermediate in pyrimidine nucleotide biosynthesis in RNA and DNA, and plays a crucial role in contemporary biology. |
| Name | orotidine |
|---|---|
| Synonym | More Synonyms |
| Description | Orotidine is an intermediate in pyrimidine nucleotide biosynthesis in RNA and DNA, and plays a crucial role in contemporary biology. |
|---|---|
| Related Catalog | |
| Target |
Human Endogenous Metabolite |
| References |
| Density | 1.8±0.1 g/cm3 |
|---|---|
| Melting Point | 200ºC |
| Molecular Formula | C10H12N2O8 |
| Molecular Weight | 288.211 |
| Exact Mass | 288.059357 |
| PSA | 162.08000 |
| LogP | -1.24 |
| Index of Refraction | 1.678 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| HS Code | 2934999090 |
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
|
Pyrophosphate interactions at the transition states of Plasmodium falciparum and human orotate phosphoribosyltransferases.
J. Am. Chem. Soc. 132(25) , 8787-94, (2010) Orotate phosphoribosyltransferases from Plasmodium falciparum and human sources (PfOPRT and HsOPRT) use orotidine as a slow substrate in the pyrophosphorolysis reaction. With orotidine, intrinsic kine... |
|
|
The allopurinol load test lacks specificity for primary urea cycle defects but may indicate unrecognized mitochondrial disease.
J. Inherit. Metab. Dis. 22(2) , 174-84, (1999) Thirty-three children ranging from 2 weeks to 12 years of age were selected for allopurinol loading, 16 on the basis of an increased urinary ourotate excretion detected by routine organic acid analysi... |
|
|
Orotidine accumulation in human erythrocytes during allopurinol therapy: association with high urinary oxypurinol-7-riboside concentrations in renal failure and in the Lesch-Nyhan syndrome.
Clin. Sci. 80(3) , 191-7, (1991) 1. A compound identified as orotidine has been found in the erythrocytes of all subjects on allopurinol. 2. The erythrocyte orotidine concentrations were much higher in patients with renal failure or ... |
| UNII:B350MC02GZ |
| 3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,6-dioxopyrimidine-4-carboxylic acid |
| 1,2,3,6-Tetrahydro-2,6-dioxo-3-b-D-ribofuranosyl-4-pyrimidinecarboxylic Acid |
| 6-Carboxyuridin |
| 3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl]-2,6-diketo-pyrimidine-4-carboxylic acid |
| Uridine-6-carboxylic acid |
| 3-b-D-Ribofuranosylorotic Acid |
| Orotidine |
| Uridine, 6-carboxy- |
| Orotidine (Uridine-6-carboxylic acid) |
| 6-Carboxyuridine |
| URIDIN-6-CARBOXYLIC ACID |