4-hydroxy-8-methoxy-1-methyl-2(1H)-quinolinone

Modify Date: 2025-10-01 10:45:25

4-hydroxy-8-methoxy-1-methyl-2(1H)-quinolinone Structure
4-hydroxy-8-methoxy-1-methyl-2(1H)-quinolinone structure
Common Name 4-hydroxy-8-methoxy-1-methyl-2(1H)-quinolinone
CAS Number 3148-27-4 Molecular Weight 205.21
Density N/A Boiling Point N/A
Molecular Formula C11H11NO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 4-hydroxy-8-methoxy-1-methyl-2(1H)-quinolinone

 Chemical & Physical Properties

Molecular Formula C11H11NO3
Molecular Weight 205.21
InChIKey IHANDTHWZGLKJW-UHFFFAOYSA-N
SMILES COc1cccc2c(O)cc(=O)n(C)c12

 Bioassay

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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae sp...
Source: NMMLSC
Target: MEP2 [Saccharomyces cerevisiae]
External Id: UNM_TOR_Pathway_HTS_in_Saccharomyces_cerevisiae_specifically_MEP2_ThirdCherryPick
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
Name: Flow Cytometric HTS Screen for inhibitors of the ABC transporter ABCB6 for Validation...
Source: NMMLSC
Target: ATP-binding cassette sub-family B member 6, mitochondrial [Homo sapiens]
External Id: UNMCMD_ABCB6_1o_ValidationSet
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