4-Thiazolidinone,2-thioxo-3-[3-(trifluoromethyl)phenyl]

Modify Date: 2025-09-18 22:33:45

4-Thiazolidinone,2-thioxo-3-[3-(trifluoromethyl)phenyl] Structure
4-Thiazolidinone,2-thioxo-3-[3-(trifluoromethyl)phenyl] structure
Common Name 4-Thiazolidinone,2-thioxo-3-[3-(trifluoromethyl)phenyl]
CAS Number 315-08-2 Molecular Weight 277.28600
Density 1.58g/cm3 Boiling Point 338.1ºC at 760mmHg
Molecular Formula C10H6F3NOS2 Melting Point N/A
MSDS N/A Flash Point 158.3ºC

 Names

Name 2-sulfanylidene-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-4-one

 Chemical & Physical Properties

Density 1.58g/cm3
Boiling Point 338.1ºC at 760mmHg
Molecular Formula C10H6F3NOS2
Molecular Weight 277.28600
Flash Point 158.3ºC
Exact Mass 276.98400
PSA 77.70000
LogP 3.13510
Index of Refraction 1.633
InChIKey MRDJXDJVVCNDND-UHFFFAOYSA-N
SMILES O=C1CSC(=S)N1c1cccc(C(F)(F)F)c1

 Safety Information

HS Code 2934999090

 Synthetic Route

~%

4-Thiazolidinone,2-thioxo-3-[3-(trifluoromethyl)phenyl] Structure

4-Thiazolidinon...

CAS#:315-08-2

Literature: US2011/105565 A1, ; Page/Page column 26-28 ;

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4-Thiazolidinone,2-thioxo-3-[3-(trifluoromethyl)phenyl] Structure

4-Thiazolidinon...

CAS#:315-08-2

Literature: Journal of Medicinal Chemistry, , vol. 51, # 24 p. 7843 - 7854

~%

4-Thiazolidinone,2-thioxo-3-[3-(trifluoromethyl)phenyl] Structure

4-Thiazolidinon...

CAS#:315-08-2

Literature: US2011/105565 A1, ;

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Bioassay

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Name: Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: HCMV UL50
External Id: HMS1262
Name: Inhibition of HIV1 3B gp41 six-helix bundle formation after 30 mins by native-polyacr...
Source: ChEMBL
Target: N/A
External Id: CHEMBL1017070
Name: Cytotoxicity against human MT2 cells after 4 days by XTT assay
Source: ChEMBL
Target: MT2
External Id: CHEMBL1017068
Name: HIV Enzyme Data
Source: NIAID
Target: N/A
External Id: HIV Enzyme Data
Name: Selectivity index, ratio of CC50 for human MT2 cells to EC50 for HIV1 3B
Source: ChEMBL
Target: N/A
External Id: CHEMBL1017069
Name: Antiviral activity against HIV1 3B in human MT2 cells assessed as inhibition of p24 a...
Source: ChEMBL
Target: Human immunodeficiency virus 1
External Id: CHEMBL1017067
Name: Cell-based high throughput primary assay to identify activators of GPR151
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id: GPR151_PHUNTER_AG_LUMI_1536_1X%ACT
Name: AlphaScreen-based biochemical high throughput primary assay to identify activators of...
Source: The Scripps Research Institute Molecular Screening Center
Target: N/A
External Id: FBW7_ACT_ALPHA_1536_1X%ACT PRUN
Name: AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of...
Source: The Scripps Research Institute Molecular Screening Center
External Id: MITF_INH_Alpha_1536_1X%INH PRUN
Name: HIV Cellular Data
Source: NIAID
Target: N/A
External Id: HIV Cellular Data
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