FSL-1

Modify Date: 2025-08-26 11:35:59

FSL-1 Structure
FSL-1 structure
Common Name FSL-1
CAS Number 322455-70-9 Molecular Weight 1666.158
Density 1.2±0.1 g/cm3 Boiling Point 1659.8±65.0 °C at 760 mmHg
Molecular Formula C84H140N14O18S Melting Point N/A
MSDS USA Flash Point 957.6±34.3 °C

 Use of FSL-1


FSL-1 is a TLR2/6 agonist (also a putative TLR10 ligand). FSL-1 activates NF-κB. FSL-1 induces pro-inflammatory cytokines including IL-8, IL-1β, CCL20 and TNF-α in vitro. FSL-1 synergizes with IFNγ to induce CXCL10 release from melanoma cells.

 Names

Name S-[(2R)-2,3-Bis(palmitoyloxy)propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-L-phenylalanine
Synonym More Synonyms

 FSL-1 Biological Activity

Description FSL-1 is a TLR2/6 agonist (also a putative TLR10 ligand). FSL-1 activates NF-κB. FSL-1 induces pro-inflammatory cytokines including IL-8, IL-1β, CCL20 and TNF-α in vitro. FSL-1 synergizes with IFNγ to induce CXCL10 release from melanoma cells.
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 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 1659.8±65.0 °C at 760 mmHg
Molecular Formula C84H140N14O18S
Molecular Weight 1666.158
Flash Point 957.6±34.3 °C
Exact Mass 1665.019043
LogP 15.83
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.553

 Safety Information

RIDADR NONH for all modes of transport

 Synonyms

S-[(2R)-2,3-Bis(palmitoyloxy)propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-L-phenylalanine
L-Phenylalanine, S-[(2R)-2,3-bis[(1-oxohexadecyl)oxy]propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-
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