1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d74

Modify Date: 2022-08-21 13:23:02

1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d74 Structure
1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d74 structure
Common Name 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d74
CAS Number 326495-38-9 Molecular Weight 864.60
Density N/A Boiling Point N/A
Molecular Formula C44H14D74NO8P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d74


1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d74 is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-gly

 Names

Name 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d74

  Biological Activity

Description 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d74 is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-gly
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[3].
References

[1]. Andrew D Miller. Delivery of RNAi therapeutics: work in progress. Expert Rev Med Devices. 2013 Nov;10(6):781-811.

[2]. Jayesh A Kulkarni, et al. On the role of helper lipids in lipid nanoparticle formulations of siRNA. Nanoscale. 2019 Nov 21;11(45):21733-21739.

[3]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

 Chemical & Physical Properties

Molecular Formula C44H14D74NO8P
Molecular Weight 864.60