WDR5-IN-6

Modify Date: 2025-09-17 20:16:47

WDR5-IN-6 Structure
WDR5-IN-6 structure
Common Name WDR5-IN-6
CAS Number 326901-92-2 Molecular Weight 327.19
Density N/A Boiling Point N/A
Molecular Formula C13H8Cl2N2O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of WDR5-IN-6


WDR5-IN-6 is a WDR5 inhibitor, targeting to WBM site. WDR5-IN-6 inhibits cell proliferation of neuroblastoma cell lines with potent anti-tumor activity. WDR5-IN-6 shows high synergy with OICR-9429 (HY-16993), a WDR5 inhibitor targeting to WIN site. WDR5-IN-6 can be used for reasearch in neuroblastoma[1].

 Names

Name WDR5-IN-6

 WDR5-IN-6 Biological Activity

Description WDR5-IN-6 is a WDR5 inhibitor, targeting to WBM site. WDR5-IN-6 inhibits cell proliferation of neuroblastoma cell lines with potent anti-tumor activity. WDR5-IN-6 shows high synergy with OICR-9429 (HY-16993), a WDR5 inhibitor targeting to WIN site. WDR5-IN-6 can be used for reasearch in neuroblastoma[1].
Related Catalog
Target

WDR5[1]

References

[1]. Han QL, et al. Discovery, evaluation and mechanism study of WDR5-targeted small molecular inhibitors for neuroblastoma. Acta Pharmacol Sin. 2023 Apr;44(4):877-887.  

 Chemical & Physical Properties

Molecular Formula C13H8Cl2N2O2S
Molecular Weight 327.19
InChIKey PXUHMEZESKEPKJ-UHFFFAOYSA-N
SMILES O=S(=O)(c1cc(Cl)ccc1Cl)n1cnc2ccccc21
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