Dapsone hydroxylamine

Modify Date: 2024-01-21 05:54:46

Dapsone hydroxylamine structure	Common Name	Dapsone hydroxylamine
	CAS Number	32695-27-5	Molecular Weight	264.30000
	Density	1.464g/cm3	Boiling Point	531.1ºC at 760mmHg
	Molecular Formula	C₁₂H₁₂N₂O₃S	Melting Point	194ºC dec.
	MSDS	N/A	Flash Point	275ºC

Use of Dapsone hydroxylamine

Dapsone hydroxylamine (DDS-NOH) induces methemoglobinemia. Dapsone hydroxylamine inhibits catalase (CAT) activity and reactive oxygen species generation. Dapsone hydroxylamine also has anti-inflammatory activity[1].

Name	Dapsone Hydroxylamine
Synonym	More Synonyms

Description	Dapsone hydroxylamine (DDS-NOH) induces methemoglobinemia. Dapsone hydroxylamine inhibits catalase (CAT) activity and reactive oxygen species generation. Dapsone hydroxylamine also has anti-inflammatory activity[1].
Related Catalog	Research Areas >> Inflammation/Immunology
References	[1]. Albuquerque RV, et al. In Vitro Protective Effect and Antioxidant Mechanism of Resveratrol Induced by Dapsone Hydroxylamine in Human Cells. PLoS One. 2015 Aug 18;10(8):e0134768. [2]. Wozel G, et al. Dapsone hydroxylamine inhibits the LTB4-induced chemotaxis of polymorphonuclear leukocytes into human skin: results of a pilot study. Inflamm Res. 1997 Oct;46(10):420-2.

Description

Related Catalog

Research Areas >> Inflammation/Immunology

References

[1]. Albuquerque RV, et al. In Vitro Protective Effect and Antioxidant Mechanism of Resveratrol Induced by Dapsone Hydroxylamine in Human Cells. PLoS One. 2015 Aug 18;10(8):e0134768.

[2]. Wozel G, et al. Dapsone hydroxylamine inhibits the LTB4-induced chemotaxis of polymorphonuclear leukocytes into human skin: results of a pilot study. Inflamm Res. 1997 Oct;46(10):420-2.

Density	1.464g/cm3
Boiling Point	531.1ºC at 760mmHg
Melting Point	194ºC dec.
Molecular Formula	C₁₂H₁₂N₂O₃S
Molecular Weight	264.30000
Flash Point	275ºC
Exact Mass	264.05700
PSA	100.80000
LogP	3.63770
Index of Refraction	1.69
Storage condition	Amber Vial, -20°C Freezer
Stability	Light Sensitive, Temperature Sensitive

HS Code	2922199090

Benzenamine,4-[...

CAS#:1948-92-1

~80%

Dapsone hydroxy...

CAS#:32695-27-5

Literature: Vyas, Piyush M.; Roychowdhury, Sanjoy; Woster, Patrick M.; Svensson, Craig K. Biochemical Pharmacology, 2005 , vol. 70, # 2 p. 275 - 286

4,4'-Diaminodip...

CAS#:80-08-0

Dapsone hydroxy...

CAS#:32695-27-5

Literature: Clinical Pharmacology and Therapeutics, , vol. 58, # 5 p. 556 - 566

Precursor 2
CAS#:1948-92-1 Benzenamine,4-[... CAS#:80-08-0 4,4'-Diaminodip...
DownStream 1
CAS#:80-08-0 4,4'-Diaminodip...

HS Code	2922199090
Summary	2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%