6-Methoxy-2-methyl-1H-benz[de]isoquinoline-1,3(2H)-dione

Modify Date: 2026-08-02 13:49:09

6-Methoxy-2-methyl-1H-benz[de]isoquinoline-1,3(2H)-dione structure	Common Name	6-Methoxy-2-methyl-1H-benz[de]isoquinoline-1,3(2H)-dione
	CAS Number	3271-05-4	Molecular Weight	241.242
	Density	1.3±0.1 g/cm3	Boiling Point	431.7±28.0 °C at 760 mmHg
	Molecular Formula	C₁₄H₁₁NO₃	Melting Point	N/A
	MSDS	N/A	Flash Point	214.9±24.0 °C

Name	6-methoxy-2-methylbenzo[de]isoquinoline-1,3-dione
Synonym	More Synonyms

Density	1.3±0.1 g/cm3
Boiling Point	431.7±28.0 °C at 760 mmHg
Molecular Formula	C₁₄H₁₁NO₃
Molecular Weight	241.242
Flash Point	214.9±24.0 °C
Exact Mass	241.073898
PSA	48.30000
LogP	1.10
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.662

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QK5960000

CHEMICAL NAME :: Naphthalimide, 4-methoxy-N-methyl-

CAS REGISTRY NUMBER :: 3271-05-4

BEILSTEIN REFERENCE NO. :: 1534374

LAST UPDATED :: 199712

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C14-H11-N-O3

MOLECULAR WEIGHT :: 241.26

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 15 gm/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - lacrimation Behavioral - somnolence (general depressed activity) Skin and Appendages - hair

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 7700 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Body fluid assay

TEST SYSTEM :: Rodent - rat Bacteria - Salmonella typhimurium

DOSE/DURATION :: 12600 mg/kg/7D (Continuous)

REFERENCE :: AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 16,119,1987

HS Code	2933990090

Sodium Methylate

CAS#:124-41-4

4-chloro-N-meth...

CAS#:4118-33-6

~88%

6-Methoxy-2-met...

CAS#:3271-05-4

Learn More

Literature: Adam, Waldemar; Qian, Xuhong; Saha-Moeller, Chantu R. Tetrahedron, 1993 , vol. 49, # 2 p. 417 - 422

Methanol

CAS#:67-56-1

4-nitro-N-methy...

CAS#:39061-36-4

~96%

6-Methoxy-2-met...

CAS#:3271-05-4

Learn More

Literature: Demets, Gregoire J.-F.; Triboni, Eduardo R.; Alvarez, Emiliano B.; Arantes, Guilherme M.; Filho, Pedro Berci; Politi, Mario J. Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 2006 , vol. 63, # 1 p. 220 - 226

Precursor 4
CAS#:124-41-4 Sodium Methylate CAS#:4118-33-6 4-chloro-N-meth... CAS#:67-56-1 Methanol CAS#:39061-36-4 4-nitro-N-methy...
DownStream 0

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Name: Inhibition of recombinant human PRMT5 expressed in Sf9 cells using histone H4 peptide...
Source: ChEMBL
Target: Protein arginine N-methyltransferase 5
External Id: CHEMBL3112256

Name: AlphaScreen-based biochemical high throughput counterscreen assay to identify compoun...
Source: The Scripps Research Institute Molecular Screening Center
External Id: LysRS_INH_Alpha_1536_3X%INH CSRUN

Name: Inhibition of recombinant human PRMT1 expressed in Escherichia coli using histone H4 ...
Source: ChEMBL
Target: Protein arginine N-methyltransferase 1
External Id: CHEMBL3112258

Name: Cytotoxicity against human VCaP cells after 7 days by Alamar blue staining method
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL3112259

Name: Cytotoxicity against human LAPC4 cells after 7 days by Alamar blue staining method
Source: ChEMBL
Target: LAPC4
External Id: CHEMBL3112260

Name: AlphaScreen-based biochemical high throughput dose response assay to identify inhibit...
Source: The Scripps Research Institute Molecular Screening Center
External Id: MITF_INH_Alpha_1536_3XIC50 DRUN

Name: FRET-based biochemical high throughput dose response assay to identify inhibitors of ...
Source: The Scripps Research Institute Molecular Screening Center
External Id: MITF_INH_FRET_1536_3XIC50 DCSRUN

Name: Cell-based high throughput primary assay to identify activators of GPR151
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id: GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

Name: AlphaScreen-based biochemical high throughput primary assay to identify activators of...
Source: The Scripps Research Institute Molecular Screening Center
Target: N/A
External Id: FBW7_ACT_ALPHA_1536_1X%ACT PRUN

Name: AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of...
Source: The Scripps Research Institute Molecular Screening Center
External Id: MITF_INH_Alpha_1536_1X%INH PRUN

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Mikawhite AT CONC

4-Methoxy-naphthalsaeure-N-methylimid

NAPHTHALIMIDE,4-METHOXY-N-METHYL

6-methoxy-2-methyl-1H-benz(de)isoquinoline-1,3(2H)-dione

EINECS 221-895-6

6-methoxy-2-methyl-benzo[de]isoquinoline-1,3-dione

Mikawhite AT

4-Methoxy-N-methylnaphthalimide

Fluorescent Brightener 162

Fluorescent Brightening Agent 162

C.I. Fluorescent Brightener 162

5-Methoxy-N-methyl-1,8-naphthalindicarboximid

N-Methyl-4-methoxynaphthalimide

6-Methoxy-2-methyl-1H-benzo[de]isoquinoline-1,3(2H)-dione

4-methoxy-N-methyl-1,8-naphthalimide

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6-Methoxy-2-methyl-1H-benz[de]isoquinoline-1,3(2H)-dione

Names

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Safety Information

Synthetic Route

Precursor & DownStream

Customs

Bioassay

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.