RU-TRAAK-1

Modify Date: 2024-02-18 22:47:04

RU-TRAAK-1 Structure
RU-TRAAK-1 structure
Common Name RU-TRAAK-1
CAS Number 328034-85-1 Molecular Weight 443.538
Density 1.2±0.1 g/cm3 Boiling Point 561.3±60.0 °C at 760 mmHg
Molecular Formula C27H29N3O3 Melting Point N/A
MSDS N/A Flash Point 293.3±32.9 °C

 Use of RU-TRAAK-1


A poorly reversible TRAAK inhibitor, shows no activity for non-K2P channels (Kv1.2, Slo1 and GIRK2).

 Names

Name 3-{[(E)-(3,5-Di-tert-butyl-4-hydroxyphenyl)methylene]amino}-2-(2-furyl)quinazolin-4(3H)-one
Synonym More Synonyms

 RU-TRAAK-1 Biological Activity

Description A poorly reversible TRAAK inhibitor, shows no activity for non-K2P channels (Kv1.2, Slo1 and GIRK2).
References References 1. Su Z, et al. Proc Natl Acad Sci U S A. 2016 May 17;113(20):5748-53. View Related Products by Target Potassium Channel

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 561.3±60.0 °C at 760 mmHg
Molecular Formula C27H29N3O3
Molecular Weight 443.538
Flash Point 293.3±32.9 °C
Exact Mass 443.220886
LogP 6.61
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.600

 Synonyms

2-(2-Furyl)-3-{(E)-[4-hydroxy-3,5-bis(2-methyl-2-propanyl)benzylidene]amino}-4(3H)-quinazolinone
4(3H)-Quinazolinone, 3-[[(1E)-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]amino]-2-(2-furanyl)-
3-{[(E)-(3,5-Di-tert-butyl-4-hydroxyphenyl)methylene]amino}-2-(2-furyl)quinazolin-4(3H)-one