NSC 630668

Modify Date: 2024-01-12 08:43:11

NSC 630668 Structure
NSC 630668 structure
Common Name NSC 630668
CAS Number 330846-35-0 Molecular Weight 822.859
Density 1.3±0.1 g/cm3 Boiling Point N/A
Molecular Formula C36H54N8O14 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NSC 630668


NSC 630668 is a Hsc70 inhibitor that inhibits the endogenous and DnaJ-stimulated ATPase activity of hsc70; blocks the hsc70-mediated translocation of a preprotein into yeast endoplasmic reticulum-derived microsomal vesicles.

 Names

Name Bis(6-{5-[(ethoxycarbonyl)carbamoyl]-2,4-dioxo-3,4-dihydro-1(2H)-pyrimidinyl}hexyl) 1,6-hexanediylbiscarbamate
Synonym More Synonyms

 NSC 630668 Biological Activity

Description NSC 630668 is a Hsc70 inhibitor that inhibits the endogenous and DnaJ-stimulated ATPase activity of hsc70; blocks the hsc70-mediated translocation of a preprotein into yeast endoplasmic reticulum-derived microsomal vesicles.
References References 1. Fewell SW, et al. J Biol Chem. 2001 Jan 12;276(2):910-4. 2. Fewell SW, et al. J Biol Chem. 2004 Dec 3;279(49):51131-40. View Related Products by Target Heat Shock Protein (HSP)

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Molecular Formula C36H54N8O14
Molecular Weight 822.859
Exact Mass 822.375977
LogP 1.43
Index of Refraction 1.532

 Synonyms

Carbamic acid, N,N'-1,6-hexanediylbis-, bis[6-[5-[[(ethoxycarbonyl)amino]carbonyl]-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl]hexyl] ester
Bis(6-{5-[(ethoxycarbonyl)carbamoyl]-2,4-dioxo-3,4-dihydro-1(2H)-pyrimidinyl}hexyl) 1,6-hexanediylbiscarbamate
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