1,3-DIOXOLO(4,5-g)QUINAZOLIN-6(5H)-ONE, 5-(1-METHYLETHYL)-8-PHENYL-

Modify Date: 2024-01-12 09:18:22

1,3-DIOXOLO(4,5-g)QUINAZOLIN-6(5H)-ONE, 5-(1-METHYLETHYL)-8-PHENYL- structure	Common Name	1,3-DIOXOLO(4,5-g)QUINAZOLIN-6(5H)-ONE, 5-(1-METHYLETHYL)-8-PHENYL-
	CAS Number	33095-89-5	Molecular Weight	308.33100
	Density	1.32g/cm3	Boiling Point	486.3ºC at 760 mmHg
	Molecular Formula	C₁₈H₁₆N₂O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	247.9ºC

Name	8-phenyl-5-propan-2-yl-[1,3]dioxolo[4,5-g]quinazolin-6-one
Synonym	More Synonyms

Density	1.32g/cm3
Boiling Point	486.3ºC at 760 mmHg
Molecular Formula	C₁₈H₁₆N₂O₃
Molecular Weight	308.33100
Flash Point	247.9ºC
Exact Mass	308.11600
PSA	53.35000
LogP	3.37310
Index of Refraction	1.658

CHEMICAL IDENTIFICATION

RTECS NUMBER :: JI5050000

CHEMICAL NAME :: 1,3-Dioxolo(4,5-g)quinazolin-6(5H)-one, 5-(1-methylethyl)-8-phenyl-

CAS REGISTRY NUMBER :: 33095-89-5

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C18-H16-N2-O3

MOLECULAR WEIGHT :: 308.36

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 162 mg/kg

TOXIC EFFECTS :: Behavioral - general anesthetic Behavioral - somnolence (general depressed activity) Behavioral - changes in motor activity (specific assay)

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 34,879,1984

1-isopropyl-4-p...

CAS#:33095-91-9

~86%

1,3-DIOXOLO(4,5...

CAS#:33095-89-5

Literature: Houlihan, William J.; Cooke, George; Bochoven, Richard Van; Perrine, John; Takesue, Edward I.; Jukniewicz, E. Journal of Medicinal Chemistry, 1982 , vol. 25, # 9 p. 1110 - 1113

N-propan-2-yl-1...

CAS#:10368-14-6

1,3-DIOXOLO(4,5...

CAS#:33095-89-5

Literature: Houlihan, William J.; Cooke, George; Bochoven, Richard Van; Perrine, John; Takesue, Edward I.; Jukniewicz, E. Journal of Medicinal Chemistry, 1982 , vol. 25, # 9 p. 1110 - 1113

Urea,N-1,3-benz...

CAS#:33095-94-2

1,3-DIOXOLO(4,5...

CAS#:33095-89-5

Literature: Houlihan, William J.; Cooke, George; Bochoven, Richard Van; Perrine, John; Takesue, Edward I.; Jukniewicz, E. Journal of Medicinal Chemistry, 1982 , vol. 25, # 9 p. 1110 - 1113

Benzo[d][1,3]di...

CAS#:14268-66-7

1,3-DIOXOLO(4,5...

CAS#:33095-89-5

Literature: Houlihan, William J.; Cooke, George; Bochoven, Richard Van; Perrine, John; Takesue, Edward I.; Jukniewicz, E. Journal of Medicinal Chemistry, 1982 , vol. 25, # 9 p. 1110 - 1113

Precursor 4
CAS#:33095-91-9 1-isopropyl-4-p... CAS#:10368-14-6 N-propan-2-yl-1... CAS#:33095-94-2 Urea,N-1,3-benz... CAS#:14268-66-7 Benzo[d][1,3]di...
DownStream 0

5-Isopropyl-8-phenyl-1,3-dioxolo(4,5-g)quinazolin-6(5H)-one

1-isopropyl-4-phenyl-6,7-methylenedioxy-2(1H)-quinazolinone

1-isopropyl-6,7-methylenedioxy-4-phenylquinazolin-2(1H)-one

1-Isopropyl-4-phenyl-6,7-methylendioxy-2(1H)chinazolinon

1,3-DIOXOLO(4,5-g)QUINAZOLIN-6(5H)-ONE,5-(1-METHYLETHYL)-8-PHENYL

Dichloromethane
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sodium carbonate
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Silicon dioxide
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4-(4-Piperidinyl)morpholine dihydrochloride
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Diclofenac sodium
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1,3-DIOXOLO(4,5-g)QUINAZOLIN-6(5H)-ONE, 5-(1-METHYLETHYL)-8-PHENYL-

Names

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Synthetic Route

Precursor & DownStream

Synonyms