2'-O-MOE-N6-Bz-rA

Modify Date: 2024-01-10 22:31:51

2'-O-MOE-N6-Bz-rA Structure
2'-O-MOE-N6-Bz-rA structure
Common Name 2'-O-MOE-N6-Bz-rA
CAS Number 333335-93-6 Molecular Weight 429.43
Density N/A Boiling Point N/A
Molecular Formula C20H23N5O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2'-O-MOE-N6-Bz-rA


N6-Benzoyl-2'-O-(2-methoxyethyl)adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name N-[9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)oxolan-2-yl]purin-6-yl]benzamide
Synonym More Synonyms

 2'-O-MOE-N6-Bz-rA Biological Activity

Description N6-Benzoyl-2'-O-(2-methoxyethyl)adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C20H23N5O6
Molecular Weight 429.43
Exact Mass 429.16500
PSA 144.34000
LogP 0.74480

 Synonyms

Adenosine,N-benzoyl-2'-O-(2-methoxyethyl)
2'-O-MOE-N6-Bz-rA