L-histidyl-L-prolinamide

Modify Date: 2024-01-17 13:55:37

L-histidyl-L-prolinamide Structure
L-histidyl-L-prolinamide structure
Common Name L-histidyl-L-prolinamide
CAS Number 33605-69-5 Molecular Weight 251.28500
Density 1.378g/cm3 Boiling Point 678ºC at 760mmHg
Molecular Formula C11H17N5O2 Melting Point N/A
MSDS N/A Flash Point 363.9ºC

 Use of L-histidyl-L-prolinamide


Histidylprolineamide (His-pro-amide) is a reactive amide, an intermediate in the histidine metabolic pathway[1].

 Names

Name (2S)-1-[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carboxamide
Synonym More Synonyms

 L-histidyl-L-prolinamide Biological Activity

Description Histidylprolineamide (His-pro-amide) is a reactive amide, an intermediate in the histidine metabolic pathway[1].
Related Catalog
References

[1]. T Matsui, et al. Metabolism of thyrotropin releasing hormone in brain extracts. Isolation and characterization of an imidopeptidase for histidylprolineamide. J Biol Chem. 1979 Apr 10;254(7):2439-45.   

 Chemical & Physical Properties

Density 1.378g/cm3
Boiling Point 678ºC at 760mmHg
Molecular Formula C11H17N5O2
Molecular Weight 251.28500
Flash Point 363.9ºC
Exact Mass 251.13800
PSA 118.10000
LogP 0.09430
Index of Refraction 1.625

 Synthetic Route

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L-histidyl-L-prolinamide Structure

L-histidyl-L-pr...

CAS#:33605-69-5

Literature: Georgetown University Patent: US7202279 B1, 2007 ; Location in patent: Page/Page column 48 ;

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L-histidyl-L-prolinamide Structure

L-histidyl-L-pr...

CAS#:33605-69-5

Literature: Sakura; Hirose; Nishijima; Hashimoto; Okabe; Mi amori; Sato Chemical and Pharmaceutical Bulletin, 1989 , vol. 37, # 11 p. 3125 - 3127

 Synonyms

His-Pro-NH2
Histidylprolinamid
1-histidyl-proline amide
L-histidinyl-L-prolinamide
L-histidyl-L-prolinamide
histidyl proline amide
His-pro-amide
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