2,4(1H,3H)-Pyrimidinedione,1-b-D-arabinofuranosyl-5-bromo

Modify Date: 2026-07-23 07:57:11

2,4(1H,3H)-Pyrimidinedione,1-b-D-arabinofuranosyl-5-bromo Structure
2,4(1H,3H)-Pyrimidinedione,1-b-D-arabinofuranosyl-5-bromo structure
Common Name 2,4(1H,3H)-Pyrimidinedione,1-b-D-arabinofuranosyl-5-bromo
CAS Number 3370-69-2 Molecular Weight 323.10
Density 2.043g/cm3 Boiling Point N/A
Molecular Formula C9H11BrN2O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2,4(1H,3H)-Pyrimidinedione,1-b-D-arabinofuranosyl-5-bromo


1-β-D-Arabinofuranosyl-5-bromo-2,4(1H,3H)-pyrimidinedione is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name 5-bromo-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Synonym More Synonyms

  Biological Activity

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description 1-β-D-Arabinofuranosyl-5-bromo-2,4(1H,3H)-pyrimidinedione is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 2.043g/cm3
Molecular Formula C9H11BrN2O6
Molecular Weight 323.10
Exact Mass 321.98000
PSA 124.78000
InChIKey AGFIRQJZCNVMCW-UHFFFAOYSA-N
SMILES O=c1[nH]c(=O)n(C2OC(CO)C(O)C2O)cc1Br

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

5-BroMoarabinouridine

  | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What are the uses of 5-bromo-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione?
A: Main uses of 5-bromo-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione: 1-β-D-Arabinofuranosyl-5-bromo-2,4(1H,3H)-pyrimidinedione is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Q: What is the CAS number of 5-bromo-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione?
A: CAS number of 5-bromo-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione is 3370-69-2.
Q: What English synonyms does 5-bromo-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione have?
A: English synonyms of 5-bromo-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione: 5-BroMoarabinouridine.
Q: What is the SMILES notation of 5-bromo-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione?
A: SMILES notation of 5-bromo-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione is O=c1[nH]c(=O)n(C2OC(CO)C(O)C2O)cc1Br.
Q: What is the polar surface area (PSA) of 5-bromo-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione?
A: Polar surface area (PSA) of 5-bromo-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione is 124.78000.
Q: What is the molecular weight of 5-bromo-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione?
A: Molecular weight of 5-bromo-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione is 323.10.
Q: What is the Chinese name of 3370-69-2?
A: Chinese name of 3370-69-2 is 3370-69-2.
Q: What is the InChIKey of 5-bromo-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione?
A: InChIKey of 5-bromo-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione is AGFIRQJZCNVMCW-UHFFFAOYSA-N.
Q: What is the molecular formula of 5-bromo-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione?
A: Molecular formula of 5-bromo-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione is C9H11BrN2O6.
Q: What is the English name of 5-bromo-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione?
A: The English name of 5-bromo-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione is 5-bromo-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione.

 factory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

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