3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(4-methoxyphenyl)-2,6-dimethyl-, diethyl ester (9CI)

Modify Date: 2026-07-16 20:58:37

3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(4-methoxyphenyl)-2,6-dimethyl-, diethyl ester (9CI) structure	Common Name	3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(4-methoxyphenyl)-2,6-dimethyl-, diethyl ester (9CI)
	CAS Number	34014-60-3	Molecular Weight	359.41600
	Density	1.132g/cm3	Boiling Point	481.7ºC at 760 mmHg
	Molecular Formula	C₂₀H₂₅NO₅	Melting Point	N/A
	MSDS	N/A	Flash Point	245.1ºC

Name	diethyl 4-(4-methoxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
Synonym	More Synonyms

Density	1.132g/cm3
Boiling Point	481.7ºC at 760 mmHg
Molecular Formula	C₂₀H₂₅NO₅
Molecular Weight	359.41600
Flash Point	245.1ºC
Exact Mass	359.17300
PSA	73.86000
LogP	3.38500
Index of Refraction	1.525
InChIKey	QCJJMPZWBYORGR-UHFFFAOYSA-N
SMILES	CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1c1ccc(OC)cc1

CHEMICAL IDENTIFICATION

RTECS NUMBER :: US7979000

CHEMICAL NAME :: 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(p-methoxyphenyl)-2,6-dimethyl-, diethyl ester

CAS REGISTRY NUMBER :: 34014-60-3

BEILSTEIN REFERENCE NO. :: 0043785

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C20-H25-N-O5

MOLECULAR WEIGHT :: 359.46

WISWESSER LINE NOTATION :: T6M DHJ B1 CVO2 DR DO1& EVO2 F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#01323

HS Code	2933399090

Ethyl acetoacetate

CAS#:141-97-9

4-Methoxybenzal...

CAS#:123-11-5

~97%

3,5-Pyridinedic...

CAS#:34014-60-3

Learn More

Literature: Sivamurugan; Vinu; Palanichamy; Murugesan Heteroatom Chemistry, 2006 , vol. 17, # 4 p. 267 - 271

Ammonium acetate

CAS#:631-61-8

Ethyl acetoacetate

CAS#:141-97-9

4-Methoxybenzal...

CAS#:123-11-5

~80%

3,5-Pyridinedic...

CAS#:34014-60-3

Learn More

Literature: Murthy; Rajack, Abdul; Taraka Ramji; Jeson Babu; Praveen, Ch.; Aruna Lakshmi Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 18 p. 6016 - 6023

Ethyl acetoacetate

CAS#:141-97-9

4-Methoxybenzal...

CAS#:123-11-5

Urea

CAS#:57-13-6

~36%

ETHYL 4-(4-METH...

CAS#:161374-07-8

Detail Learn More

Literature: Angeles-Beltran, Deyanira; Lomas-Romero, Leticia; Lara-Corona, Victor H.; Gonzalez-Zamora, Eduardo; Negron-Silva, Guillermo Molecules, 2006 , vol. 11, # 10 p. 731 - 738

4-Methoxybenzal...

CAS#:123-11-5

3,5-Pyridinedic...

CAS#:34014-60-3

Learn More

Literature: Vanden Eynde; D'Orazio; Mayence; Maquestiau; Anders Tetrahedron, 1992 , vol. 48, # 7 p. 1263 - 1268

Ethyl acetoacetate

CAS#:141-97-9

Ethyl (2Z)-3-am...

CAS#:626-34-6

4-Methoxybenzal...

CAS#:123-11-5

3,5-Pyridinedic...

CAS#:34014-60-3

Learn More

Literature: Borsche; Hahn Justus Liebigs Annalen der Chemie, 1939 , vol. 537, p. 219,242 Full Text Show Details Berson; Brown Journal of the American Chemical Society, 1955 , vol. 77, p. 444,446

Ethyl (2Z)-3-am...

CAS#:626-34-6

4-Methoxybenzal...

CAS#:123-11-5

3,5-Pyridinedic...

CAS#:34014-60-3

Learn More

Literature: Da Silva; Goncalves; Ferre; Sena; Coelho; Junior, J. Jones Heterocyclic Communications, 2009 , vol. 15, # 1 p. 57 - 59

ethyl 3-aminocr...

CAS#:41867-20-3

N-[chloro(4-met...

CAS#:140445-85-8

3,5-Pyridinedic...

CAS#:34014-60-3

Learn More

Literature: Vanden Eynde; D'Orazio; Mayence; Maquestiau; Anders Tetrahedron, 1992 , vol. 48, # 7 p. 1263 - 1268

Precursor 7
CAS#:141-97-9 Ethyl acetoacetate CAS#:123-11-5 4-Methoxybenzal... CAS#:631-61-8 Ammonium acetate CAS#:57-13-6 Urea
CAS#:626-34-6 Ethyl (2Z)-3-am... CAS#:41867-20-3 ethyl 3-aminocr... CAS#:140445-85-8 N-[chloro(4-met...
DownStream 1
CAS#:5448-05-5 3,5-Pyridinedic...

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS

Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN

Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN

Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.

Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity

Name: Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-D-glucuron...
Source: ChEMBL
Target: Beta-glucuronidase
External Id: CHEMBL3412769

Name: Cytotoxicity against rat 3T3 cells by MTT assay
Source: ChEMBL
Target: 3T3
External Id: CHEMBL3412770

Name: Inhibition of purified bovine erythrocyte carbonic anhydrase 2 using 4-PNA as substra...
Source: ChEMBL
Target: Carbonic anhydrase 2
External Id: CHEMBL3412767

Total 137, Current Page 1 of 14

diethyl 2,6-dimethyl-4-p-methoxyphenyl-1,4-dihydropyridine-3,5-dicarboxylate

Ftorin

diethyl 1,4-dihydro-2,6-dimethyl-4-(4-methoxyphenyl)pyridine-3,5-dicarboxylate

1,4-Dihydro-2,6-dimethyl-4-(2-(trifluoromethyl)phenyl)-3,5-pyridinedicarboxylic acid diethyl ester

diethyl 2,6-dimethyl-4-(4-methoxyphenyl)-1,4-dihydropyridine-3,5-dicarboxylate

SK&Ftorin (pharmaceutical)

4-(2-Trifluoromethylphenyl)-3,5-dicarbethoxy-2,6-dimethyl-1,4-dihydropyridine

4-<2-(trifluoromethyl)phenyl>-3,5-dicarboethoxy-1,4-dihydrolutidine

diethyl 1,4-dihydro-2,6-dimethyl-4-[2-(trifluoromethyl)phenyl]3,5-pyridinedicarboxylate

3,5-dicarbethoxy-1,4-dihydro-2,6-dimethyl-4-(2-trifluoromethylphenyl)pyridine

2,6-Dimethyl-3,5-dicarbomethoxy-4-(o-trifluoromethylphenyl)-1,4-dihydropyridine [French]

diethyl 1,4-dihydro-4-(4-methoxyphenyl)-2,6-dimethylpyridine-3,5-dicarboxylate

diethyl 1,4-dihydro-2,6-dimethyl-4-(2-trifluoromethylphenyl)-pyridine-3,5-dicarboxylate

4-(4-methoxy-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester

3,5-diethoxycarbonyl-4-(4-methoxy)phenyl-2,6-dimethyl-1,4-dihydropyridine

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(4-methoxyphenyl)-2,6-dimethyl-, diethyl ester (9CI)

Names

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Safety Information

Synthetic Route

Precursor & DownStream

Customs

Bioassay

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.