(α,β,β-2H3)Histidine

Modify Date: 2024-01-06 17:28:20

(α,β,β-2H3)Histidine Structure
(α,β,β-2H3)Histidine structure
Common Name (α,β,β-2H3)Histidine
CAS Number 344299-50-9 Molecular Weight 158.17
Density 1.4±0.1 g/cm3 Boiling Point 458.9±35.0 °C at 760 mmHg
Molecular Formula C6H6D3N3O2 Melting Point N/A
MSDS N/A Flash Point 231.3±25.9 °C

 Use of (α,β,β-2H3)Histidine


DL-Histidine-d3 is the deuterium labeled DL-Histidine.

 Names

Name DL-HISTIDINE-α,β,β-D3
Synonym More Synonyms

 (α,β,β-2H3)Histidine Biological Activity

Description DL-Histidine-d3 is the deuterium labeled DL-Histidine.
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 458.9±35.0 °C at 760 mmHg
Molecular Formula C6H6D3N3O2
Molecular Weight 158.17
Flash Point 231.3±25.9 °C
Exact Mass 158.088303
PSA 92.00000
LogP -1.26
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.615

 Synonyms

histamine*2HCl
Histidine-α,β,β-d
OCHLORIDE
hystamine dihydrochloride
HISTAMINE DIHCL
Peremin
HISTAMINEHYDROCHLORIDE
histaminedichloride
Ceplene
HistaMine Chloride
(α,β,β-H)Histidine
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