Collinin

Modify Date: 2024-02-04 22:57:40

Collinin Structure
Collinin structure
Common Name Collinin
CAS Number 34465-83-3 Molecular Weight 328.40200
Density 1.092g/cm3 Boiling Point 487.1ºC at 760 mmHg
Molecular Formula C20H24O4 Melting Point N/A
MSDS N/A Flash Point 213.2ºC

 Use of Collinin


Collinin is a anti-tubercular agent, it can be isolated from leaves of Z. schinifolium. Collinin has an excellent anti-tuberculosis effect against multidrug-resistant (MDR), extensively drug-resistant (XDR) strains[1].

 Names

Name collinin
Synonym More Synonyms

 Collinin Biological Activity

Description Collinin is a anti-tubercular agent, it can be isolated from leaves of Z. schinifolium. Collinin has an excellent anti-tuberculosis effect against multidrug-resistant (MDR), extensively drug-resistant (XDR) strains[1].
Related Catalog
In Vitro Collinin在培养基中显著抑制 MDR 和 XDR 结核分枝杆菌的生长,50% 最低抑制浓度 (MIC50s) 为 3.13-6.25 µg/mL[1]。 Collinin抑制 Raw264.7 和 A549 细胞内药敏和耐药结核的生长,MIC50 为6.25-12.50 µg/mL[1]。
References

[1]. Kim S, et al. In vitro activity of collinin isolated from the leaves of Zanthoxylum schinifolium against multidrug- and extensively drug-resistant Mycobacterium tuberculosis. Phytomedicine. 2018 Jul 15;46:104-110.  

 Chemical & Physical Properties

Density 1.092g/cm3
Boiling Point 487.1ºC at 760 mmHg
Molecular Formula C20H24O4
Molecular Weight 328.40200
Flash Point 213.2ºC
Exact Mass 328.16700
PSA 48.67000
LogP 4.87310
Index of Refraction 1.542

 Synonyms

7-(3,7-dimethyl-octa-2,6-dienyloxy)-8-methoxy-chromen-2-one
7-(3,4-dichloro-phenyl)-2,4,5,7-tetrahydro-3H-[1,3]diazepino[2,1-a]isoindol-7-ol
2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}ethanol
1-Piperazineethanol,4-(3-(trifluoromethyl)phenyl)
2-(4-(3-(Trifluoromethyl)phenyl)-1-piperazinyl) ethanol
m-Trifluoro-methyl-4-phenyl-1-piperazinoethanol