Diphenylterazine

Modify Date: 2024-01-11 17:47:38

Diphenylterazine Structure
Diphenylterazine structure
Common Name Diphenylterazine
CAS Number 344940-63-2 Molecular Weight 377.44
Density N/A Boiling Point N/A
Molecular Formula C25H19N3O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Diphenylterazine


Diphenylterazine is a bioluminescence agent.

 Names

Name Diphenylterazine

 Diphenylterazine Biological Activity

Description Diphenylterazine is a bioluminescence agent.
Related Catalog
In Vitro Diphenylterazine is a bioluminescence agent. Diphenylterazine alone yields very little background, leading to excellent signal-to-background ratios. Furthermore, Diphenylterazine elicits minimal cell toxicity at millimolar concentrations. Diphenylterazine injections into untransfected BALB/c mice do not yield any background emission. The bioluminescence resulting from intraperitoneally injected Diphenylterazine displays extended kinetics[1].
Cell Assay BALB/c mice are used and transfected with cells expressing teLuc, Antares, Antares2 and FLuc by injecting cells into the tail vein of BALB/c mice. After the diminishing of the FLuc bioluminescence, 0.3 µmol Diphenylterazine or furimazine is intraperitoneally injected. Mice are imaged with a 1-min exposure per frame over a course of 20 min. The images are processed using the Fiji image analysis software and the frames with highest signals in individual experiments are used for comparison[1].
References

[1]. Yeh HW, et al. Red-shifted luciferase-luciferin pairs for enhanced bioluminescence imaging. Nat Methods. 2017 Oct;14(10):971-974.

 Chemical & Physical Properties

Molecular Formula C25H19N3O
Molecular Weight 377.44
Storage condition 2-8℃
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