7-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]oxazepine

Modify Date: 2026-07-09 16:05:24

7-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]oxazepine Structure
7-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]oxazepine structure
Common Name 7-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]oxazepine
CAS Number 3455-10-5 Molecular Weight 327.8
Density N/A Boiling Point N/A
Molecular Formula C18H18ClN3O Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 7-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]oxazepine

 Chemical & Physical Properties

Molecular Formula C18H18ClN3O
Molecular Weight 327.8
InChIKey FSRSEANZUZHDHK-UHFFFAOYSA-N
SMILES CN1CCN(C2=Nc3ccc(Cl)cc3Oc3ccccc32)CC1

 Bioassay

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Name: Activity at human histamine H3 receptor transfected in SK-N-MC cells by cAMP assay
Source: ChEMBL
Target: Histamine H3 receptor
External Id: CHEMBL870214
Name: Selectivity for human histamine H1 receptor over histamine H4 receptor
Source: ChEMBL
Target: N/A
External Id: CHEMBL870216
Name: Selectivity for human histamine H4 receptor over histamine H3 receptor
Source: ChEMBL
Target: Histamine receptor (H3 and H4)
External Id: CHEMBL871376
Name: Agonist activity at human histamine H4 receptor transfected in SK-N-MC cells
Source: ChEMBL
Target: Histamine H4 receptor
External Id: CHEMBL866003
Name: Displacement of [3H]histamine from human H4 receptor expressed in HEK cell membranes
Source: ChEMBL
Target: Histamine H4 receptor
External Id: CHEMBL1936672
Name: Agonist activity at human histamine H1 receptor transfected in SK-N-MC cells
Source: ChEMBL
Target: Histamine H1 receptor
External Id: CHEMBL866002
Name: Agonist activity at human histamine H2 receptor transfected in SK-N-MC cells
Source: ChEMBL
Target: Histamine H2 receptor
External Id: CHEMBL866001
Name: Agonist activity at human histamine H3 receptor transfected in SK-N-MC cells
Source: ChEMBL
Target: Histamine H3 receptor
External Id: CHEMBL870931
Name: Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T c...
Source: ChEMBL
Target: Histamine H4 receptor
External Id: CHEMBL934603
Name: Activity at human histamine H1 receptor transfected in COS7 cells by NF-kappaB lucife...
Source: ChEMBL
Target: Histamine H1 receptor
External Id: CHEMBL869099
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