3'-CHLORO-3'-DEOXY-5'-O-TRITYLTHYMIDINE

Modify Date: 2026-08-22 19:01:25

3'-CHLORO-3'-DEOXY-5'-O-TRITYLTHYMIDINE structure	Common Name	3'-CHLORO-3'-DEOXY-5'-O-TRITYLTHYMIDINE
	CAS Number	34627-62-8	Molecular Weight	502.99
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₉H₂₇ClN₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 3'-CHLORO-3'-DEOXY-5'-O-TRITYLTHYMIDINE

3′-Chloro-3′-deoxy-5′-O-(triphenylmethyl)thymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Summary: 1-[(2R,4S,5R)-4-Chloro-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione, also known as 3'-Chloro-3'-deoxy-5'-O-tritylthymidine, CAS number: 34627-62-8, molecular formula: C29H27ClN2O4, molecular weight: 502.99. For research-use only, not for medical or clinical usage.

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	1-[(2R,4S,5R)-4-chloro-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Synonym	More Synonyms

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description	3′-Chloro-3′-deoxy-5′-O-(triphenylmethyl)thymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Molecular Formula	C₂₉H₂₇ClN₂O₄
Molecular Weight	502.99
Exact Mass	502.16600
PSA	73.58000
LogP	5.16090
InChIKey	UPBVZHGDVFKZMX-JIMJEQGWSA-N
SMILES	Cc1cn(C2CC(Cl)C(COC(c3ccccc3)(c3ccccc3)c3ccccc3)O2)c(=O)[nH]c1=O

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 1
CAS#:42214-24-4 5-methyl-1-[4-m...
DownStream 0

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

3'-Chloro-3'-deoxy-5'-O-(triphenylmethyl)thymidine

3'-Chloro-3'-deoxy-5'-O-tritylthymidine

3'-chloro-O5'-trityl-3'-deoxy-thymidine

3'-Chlor-3'-desoxy-5'-O-tritylthymidin

5'-O-trityl-3'-chlorothymidine

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the CAS number of 1-[(2R,4S,5R)-4-chloro-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione?

A: CAS number of 1-[(2R,4S,5R)-4-chloro-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione is 34627-62-8.

Q: What is the English name of 1-[(2R,4S,5R)-4-chloro-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione?

A: The English name of 1-[(2R,4S,5R)-4-chloro-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione is 1-[(2R,4S,5R)-4-chloro-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione.

Q: What English synonyms does 1-[(2R,4S,5R)-4-chloro-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione have?

A: English synonyms of 1-[(2R,4S,5R)-4-chloro-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione: 3'-Chloro-3'-deoxy-5'-O-(triphenylmethyl)thymidine, 3'-Chloro-3'-deoxy-5'-O-tritylthymidine, 3'-chloro-O5'-trityl-3'-deoxy-thymidine, 3'-Chlor-3'-desoxy-5'-O-tritylthymidin, 5'-O-trityl-3'-chlorothymidine.

Q: What is the Chinese name of 34627-62-8?

A: Chinese name of 34627-62-8 is 34627-62-8.

Q: What is the molecular weight of 1-[(2R,4S,5R)-4-chloro-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione?

A: Molecular weight of 1-[(2R,4S,5R)-4-chloro-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione is 502.99.

Q: What are the upstream materials of 1-[(2R,4S,5R)-4-chloro-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione?

A: Related upstream materials(CAS) of 1-[(2R,4S,5R)-4-chloro-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione: 42214-24-4.

Q: What is the molecular formula of 1-[(2R,4S,5R)-4-chloro-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione?

A: Molecular formula of 1-[(2R,4S,5R)-4-chloro-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione is C29H27ClN2O4.

Q: What is the polar surface area (PSA) of 1-[(2R,4S,5R)-4-chloro-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione?

A: Polar surface area (PSA) of 1-[(2R,4S,5R)-4-chloro-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione is 73.58000.

Q: What is the SMILES notation of 1-[(2R,4S,5R)-4-chloro-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione?

A: SMILES notation of 1-[(2R,4S,5R)-4-chloro-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione is Cc1cn(C2CC(Cl)C(COC(c3ccccc3)(c3ccccc3)c3ccccc3)O2)c(=O)[nH]c1=O.

Q: What is the LogP of 1-[(2R,4S,5R)-4-chloro-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione?

A: LogP of 1-[(2R,4S,5R)-4-chloro-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione is 5.16090.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Dayang Chem (Hangzhou) Co., Ltd.

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Palmitic acid
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 3'-CHLORO-3'-DEOXY-5'-O-TRITYLTHYMIDINE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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Use of 3'-CHLORO-3'-DEOXY-5'-O-TRITYLTHYMIDINE

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3'-CHLORO-3'-DEOXY-5'-O-TRITYLTHYMIDINEfactory

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