3'-CHLORO-3'-DEOXY-5'-O-TRITYLTHYMIDINE

Modify Date: 2024-01-10 17:57:57

3'-CHLORO-3'-DEOXY-5'-O-TRITYLTHYMIDINE Structure
3'-CHLORO-3'-DEOXY-5'-O-TRITYLTHYMIDINE structure
Common Name 3'-CHLORO-3'-DEOXY-5'-O-TRITYLTHYMIDINE
CAS Number 34627-62-8 Molecular Weight 502.99
Density N/A Boiling Point N/A
Molecular Formula C29H27ClN2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3'-CHLORO-3'-DEOXY-5'-O-TRITYLTHYMIDINE


3′-Chloro-3′-deoxy-5′-O-(triphenylmethyl)thymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 1-[(2R,4S,5R)-4-chloro-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Synonym More Synonyms

 3'-CHLORO-3'-DEOXY-5'-O-TRITYLTHYMIDINE Biological Activity

Description 3′-Chloro-3′-deoxy-5′-O-(triphenylmethyl)thymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C29H27ClN2O4
Molecular Weight 502.99
Exact Mass 502.16600
PSA 73.58000
LogP 5.16090

 Precursor & DownStream

Precursor  1

DownStream  0

 Synonyms

3'-Chloro-3'-deoxy-5'-O-(triphenylmethyl)thymidine
3'-Chloro-3'-deoxy-5'-O-tritylthymidine
3'-chloro-O5'-trityl-3'-deoxy-thymidine
3'-Chlor-3'-desoxy-5'-O-tritylthymidin
5'-O-trityl-3'-chlorothymidine