Amphotericin B methyl ester hydrochloride
Modify Date: 2024-01-09 12:48:31
Amphotericin B methyl ester hydrochloride structure
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Common Name | Amphotericin B methyl ester hydrochloride | ||
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| CAS Number | 35375-29-2 | Molecular Weight | 974.56700 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C48H76ClNO17 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Amphotericin B methyl ester hydrochlorideAmphotericin B methyl ester hydrochloride is the methyl ester derivative of the polyene antibiotic Amphotericin B (A634250). Amphotericin B methyl ester hydrochloride is the cholesterol-binding compound possesses significant antifungal activity. Amphotericin B methyl ester hydrochloride disrupts HIV-1 particle production and potently inhibits HIV-1 replication[1][2]. |
| Name | methyl (1S,3R,4E,6E,8E,10E,12E,14E,16E,18S,19R,20R,21S,25R,27R,30R,31R,33S,35R,37S,38R)-3-[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-19,25,27,30,31,33,35,37-octahydroxy-18,20,21-trimethyl-23-oxo-22,39-dioxabicyclo[33.3.1]nonatriaconta-4 |
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| Synonym | More Synonyms |
| Description | Amphotericin B methyl ester hydrochloride is the methyl ester derivative of the polyene antibiotic Amphotericin B (A634250). Amphotericin B methyl ester hydrochloride is the cholesterol-binding compound possesses significant antifungal activity. Amphotericin B methyl ester hydrochloride disrupts HIV-1 particle production and potently inhibits HIV-1 replication[1][2]. |
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| Related Catalog | |
| In Vitro | Amphotericin B methyl ester hydrochloride inhibits HIV-1 particle production with no significant effect on Gag binding to the plasma membrane, Gag association with lipid rafts, or Gag multimerization[1]. |
| References |
| Molecular Formula | C48H76ClNO17 |
|---|---|
| Molecular Weight | 974.56700 |
| Exact Mass | 973.48000 |
| PSA | 308.61000 |
| LogP | 2.30240 |
| Amphotericin B,methyl ester,hydrochloride |
| AME hydrochloride |