iproclozide

Modify Date: 2025-08-25 18:08:18

iproclozide Structure
iproclozide structure
Common Name iproclozide
CAS Number 3544-35-2 Molecular Weight 242.70200
Density 1.175g/cm3 Boiling Point 336.5ºC at 760mmHg
Molecular Formula C11H15ClN2O2 Melting Point N/A
MSDS N/A Flash Point 157.3ºC

 Names

Name 2-(4-chlorophenoxy)-N'-propan-2-ylacetohydrazide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.175g/cm3
Boiling Point 336.5ºC at 760mmHg
Molecular Formula C11H15ClN2O2
Molecular Weight 242.70200
Flash Point 157.3ºC
Exact Mass 242.08200
PSA 53.85000
LogP 2.97920
Index of Refraction 1.527
InChIKey GGECDTUJZOXAAR-UHFFFAOYSA-N
SMILES CC(C)NNC(=O)COc1ccc(Cl)cc1

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AG0525000
CHEMICAL NAME :
Acetic acid, (p-chlorophenoxy)-, 2-isopropylhydrazide
CAS REGISTRY NUMBER :
3544-35-2
LAST UPDATED :
199801
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C11-H15-Cl-N2-O2
MOLECULAR WEIGHT :
242.73
WISWESSER LINE NOTATION :
GR DO1VMMY1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
550 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,394,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
278 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,394,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
178 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FMXXAJ French Medicament Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Discontinued. Volume(issue)/page/year: #59M ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
600 mg/kg
SEX/DURATION :
female 15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - abortion
REFERENCE :
AOGNAX Archivio di Ostetricia e Ginecologia. (C.C. Postale N 6/19773, Naples, Italy) V.1- 1894- Volume(issue)/page/year: 71,153,1966

 Safety Information

RIDADR UN 3249
Packaging Group III
Hazard Class 6.1(b)
HS Code 2928000090

 Synthetic Route

~%

iproclozide Structure

iproclozide

CAS#:3544-35-2

Literature: Fulcrand; Berge; Noel; et al. European Journal of Medicinal Chemistry, 1978 , vol. 13, # 2 p. 177 - 182

~%

iproclozide Structure

iproclozide

CAS#:3544-35-2

Literature: Libermann,D.; Denis,J.-C. Bulletin de la Societe Chimique de France, 1961 , p. 1952 - 1954

~%

iproclozide Structure

iproclozide

CAS#:3544-35-2

Literature: Libermann,D.; Denis,J.-C. Bulletin de la Societe Chimique de France, 1961 , p. 1952 - 1954

~%

iproclozide Structure

iproclozide

CAS#:3544-35-2

Literature: Libermann,D.; Denis,J.-C. Bulletin de la Societe Chimique de France, 1961 , p. 1952 - 1954

 Customs

HS Code 2928000090
Summary 2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

 iproclozideBioassay

View more

Name: Choleostatic liver toxicity, either proven histopathologically or where the ratio of ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3137727
Name: Severe hepatitis, defined as possibly life-threatening liver failure or through clini...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3137728
Name: Chronic liver disease either proven histopathologically, or through a chonic elevatio...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3137729
Name: Cirrhosis, proven histopathologically. Value is number of references indexed. [column...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3137730
Name: Granulomatous liver disease, proven histopathologically. Value is number of reference...
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL3137731
Name: Liver damage due to vascular disease: peliosis hepatitis, hepatic veno-occlusive dise...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3137732
Name: Steatosis, proven histopathologically. Value is number of references indexed. [column...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3137733
Name: Malignant tumor, proven histopathologically. Value is number of references indexed. [...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3137734
Name: Benign tumor, proven histopathologically. Value is number of references indexed. [col...
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL3137735
Name: Animal toxicity known. [column 'TOXIC' in source]
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL3137736
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 Synonyms

4-Chlorphenoxy-essigsaeureisopropylhydrazid
Sinderesin
Iproclozid
Iproclozide
Sursum
SOG-4
EINECS 222-589-5
PC 603
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